DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RacGAP84C and Chn2

DIOPT Version :9

Sequence 1:	NP_476704.1	Gene:	RacGAP84C / 117503	FlyBaseID:	FBgn0045843	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_001157112.1	Gene:	Chn2 / 69993	MGIID:	1917243	Length:	468	Species:	Mus musculus

Alignment Length:	264	Identity:	74/264 - (28%)
Similarity:	125/264 - (47%)	Gaps:	23/264 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 SQSHSGLLREHNFKIKSY---YYNVGNCVHCRKRIRFAMA-SLRCRACPLRCHIGCCRQLTVNCI 137
            :.:|....:.||||:.::   ::    |.:|...:...:| .:||..|.|..|..|.:.:..:|.
Mouse   205 NDNHFNYEKTHNFKVHTFRGPHW----CEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQ 265

  Fly   138 PQPQIGTKRGC--LSDYAPRVAPMVPALIVHCVTEIEARGLQQEGLYRVSSTREKCKRLRRKLLR 200
            |..:...|..|  |:..........|.::..|:.|||||||:.|||||||...|..:.::....|
Mouse   266 PDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDR 330

  Fly   201 -GKSTPHLGN--KDTHTLCCCVKDFLRQLVHPLIPIYHRRDFEEATR---HEDRLAVEMAVYLAV 259
             |:......|  .|.:.:...:|.:.|.|..|:|.......|.||.:   .::||.   ||:..:
Mouse   331 DGEKADISANIYPDINIITGALKLYFRDLPIPIITYDTYSKFIEAAKISNADERLE---AVHEVL 392

  Fly   260 LELHQAHRDTLAYLMLHWQKIAESPAVR-MTVNNLAVIFAPTLF---GDLDLTLENVVTWQRVLK 320
            :.|..||.:||.|||:|.:|:..:.... |...||.::|.|||.   .|..||..:.:.:|:::.
Mouse   393 MLLPPAHYETLRYLMIHLKKVTMNEKDNLMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIV 457

  Fly   321 VLLL 324
            .:|:
Mouse   458 QILI 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RacGAP84C	NP_476704.1	C1_1	87..139	CDD:278556	14/55 (25%)
RacGAP84C	NP_476704.1	RhoGAP_MgcRacGAP	142..330	CDD:239847	58/195 (30%)
Chn2	NP_001157112.1	SH2_a2chimerin_b2chimerin	52..138	CDD:198215
		C1_1	215..267	CDD:278556	14/55 (25%)
		RhoGAP_chimaerin	275..468	CDD:239837	57/190 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910