DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RacGAP84C and racgap1

DIOPT Version :9

Sequence 1:	NP_476704.1	Gene:	RacGAP84C / 117503	FlyBaseID:	FBgn0045843	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_001001236.1	Gene:	racgap1 / 407917	XenbaseID:	XB-GENE-943983	Length:	629	Species:	Xenopus tropicalis

Alignment Length:	275	Identity:	115/275 - (41%)
Similarity:	157/275 - (57%)	Gaps:	15/275 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 DFCSQSHSGLLREHNFKIKSYYYNVGNCVHCRKRIRFAMASLRCRACPLRCHIGCCRQLTVNCIP 138
            |.|....:|.:|.|.|..|: .....:||.|.|||:|...||:||.|.:..|..|..:..:.|||
Frog   273 DTCRTPQNGGMRLHEFVSKT-VIKPESCVPCGKRIKFGKISLKCRDCRVVAHPECRERCPLPCIP 336

  Fly   139 -----QPQIGTKRGCLSDYAPRVAPMVPALIVHCVTEIEARGLQQEGLYRVSSTREKCKRLRRKL 198
                 ..:||  .|.|:|:||..:||:|.:|||||:||:.|||.:.||||:|......|.|:.|.
Frog   337 TVGGTPVRIG--EGTLADFAPLTSPMIPPIIVHCVSEIQQRGLHETGLYRISGCDRTVKELKEKF 399

  Fly   199 LRGKSTPHLGN-KDTHTLCCCVKDFLRQLVHPLIPIYHRRDFEEATRHEDRLAVEMAVYLAVLEL 262
            |||||.|.|.. .|.|.:|..:|||||.|..||:.....|.|.||....|..:...|:|.||.||
Frog   400 LRGKSVPLLSKVDDIHAVCGFLKDFLRNLKEPLLTFRLNRVFMEAAEITDEKSSIAAIYQAVDEL 464

  Fly   263 HQAHRDTLAYLMLHWQKIAESPAVRMTVNNLAVIFAPTLFG------DLDLTLENVVTWQRVLKV 321
            ...:||||||||:|.|::|:||..:|.|:||:.:|.|||.|      |....|::......|::.
Frog   465 PAPNRDTLAYLMIHLQRVAQSPDCKMDVSNLSKVFGPTLVGHAVPDPDPMTILQDTRRQPMVVER 529

  Fly   322 LLLMPAGFWSQFLEV 336
            |:|:||.||:||:.|
Frog   530 LMLLPAEFWNQFMMV 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RacGAP84C	NP_476704.1	C1_1	87..139	CDD:278556	20/56 (36%)
RacGAP84C	NP_476704.1	RhoGAP_MgcRacGAP	142..330	CDD:239847	86/194 (44%)
racgap1	NP_001001236.1	SbcC	<8..107	CDD:223496
		C1	286..334	CDD:237996	17/48 (35%)
		RhoGAP_MgcRacGAP	345..538	CDD:239847	86/194 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	140	1.000	Domainoid score	I4716
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D184774at33208
OrthoFinder	1	1.000	-	-		FOG0004815
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4412
SonicParanoid	1	1.000	-	-		X3396
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.040