DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RacGAP84C and RhoGAP18B

DIOPT Version :9

Sequence 1:	NP_476704.1	Gene:	RacGAP84C / 117503	FlyBaseID:	FBgn0045843	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	NP_573352.2	Gene:	RhoGAP18B / 32898	FlyBaseID:	FBgn0261461	Length:	1317	Species:	Drosophila melanogaster

Alignment Length:	173	Identity:	55/173 - (31%)
Similarity:	82/173 - (47%)	Gaps:	16/173 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   158 PMVPALIVHCVTEIE-ARGLQQEGLYRVSSTREKCKRLRRKLLRGKSTPHLGNKDTHTLCCCVKD 221
            |.||..:|.....|| ...::|:||||.|..:.....||:||........|...|.|||....|.
  Fly  1138 PNVPRFVVDVCAYIEQPECIEQDGLYRASGNKVLVDELRKKLTHVYDPRWLKTDDIHTLTSLHKQ 1202

  Fly   222 FLRQLVHPLIPIYHRRDFEEATRH-EDRLAVEMAVYLAVLELHQAHRDTLAYLMLHWQKIAESPA 285
            |.|:|..|||.   :..:|...|. .|..|:| .:.||..::.:.:|.||.:|:.|..::|.:.|
  Fly  1203 FFRELTSPLIT---QEAYERLGRSLNDDAAIE-RMSLAFDDMPEPNRSTLRFLIRHLTRVAAASA 1263

  Fly   286 V-RMTVNNLAVIFAPTLFG----DLDLTLENVVTWQRVLKVLL 323
            . ||...|||:::.|.|..    .||:...|::.     |||:
  Fly  1264 SNRMPSTNLAIVWGPCLLSANQIQLDIGRMNMLA-----KVLI 1301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RacGAP84C	NP_476704.1	C1_1	87..139	CDD:278556
RacGAP84C	NP_476704.1	RhoGAP_MgcRacGAP	142..330	CDD:239847	55/173 (32%)
RhoGAP18B	NP_573352.2	RhoGAP	1141..1289	CDD:279014	47/151 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3564
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810