DRSC/TRiP Functional Genomics Resources

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Protein Alignment RacGAP84C and Racgap1

DIOPT Version :9

Sequence 1:NP_476704.1 Gene:RacGAP84C / 117503 FlyBaseID:FBgn0045843 Length:384 Species:Drosophila melanogaster
Sequence 2:NP_001240737.1 Gene:Racgap1 / 26934 MGIID:1349423 Length:628 Species:Mus musculus


Alignment Length:294 Identity:114/294 - (38%)
Similarity:162/294 - (55%) Gaps:25/294 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    54 LQDRVDMNPSGCDGLSTDGLDFCSQSHSGLLREHNFKIKSYYYNVGNCVHCRKRIRFAMASLRCR 118
            |:.|.|          ||.|.  :..::|.:|.|:|..|: .....:||.|.|||:|...||:||
Mouse   267 LEPRTD----------TDNLG--TPQNTGGMRLHDFVSKT-VIKPESCVPCGKRIKFGKLSLKCR 318

  Fly   119 ACPLRCHIGCCRQLTVNCIPQPQIGTK----RGCLSDYAPRVAPMVPALIVHCVTEIEARGLQQE 179
            .|.|..|..|..:..:.||| |.:||.    .|.|:|:..:.:||:||::|.||.|||.|||.:.
Mouse   319 DCRLVSHPECRDRCPLPCIP-PLVGTPVKIGEGMLADFVSQASPMIPAIVVSCVNEIEQRGLTEA 382

  Fly   180 GLYRVSSTREKCKRLRRKLLRGKSTPHLGN-KDTHTLCCCVKDFLRQLVHPLIPIYHRRDFEEAT 243
            ||||:|......|.|:.|.|:.|:.|.|.. .|.|.:|..:|||||.|..||:..:..:.|.||.
Mouse   383 GLYRISGCDRTVKELKEKFLKVKTVPLLSKVDDIHVICSLLKDFLRNLKEPLLTFWLSKAFMEAA 447

  Fly   244 RHEDRLAVEMAVYLAVLELHQAHRDTLAYLMLHWQKIAESPAVRMTVNNLAVIFAPTLFGDLDLT 308
            ...|......|:|.||.||.||:|||||:||:|.|::::||..:|.:.|||.:|.||:.......
Mouse   448 EITDEDNSTAAMYQAVSELPQANRDTLAFLMIHLQRVSQSPDTKMDIANLAKVFGPTIVAHTVPN 512

  Fly   309 LENVVTWQ---RVLKV---LLLMPAGFWSQFLEV 336
            .:.|..:|   |.|||   ||.:|..:|:||:.|
Mouse   513 PDPVTMFQDIKRQLKVVERLLSLPLEYWNQFMMV 546

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RacGAP84CNP_476704.1 C1_1 87..139 CDD:278556 20/51 (39%)
RhoGAP_MgcRacGAP 142..330 CDD:239847 80/198 (40%)
Racgap1NP_001240737.1 Tropomyosin 43..>108 CDD:395200
Interaction with SLC26A8. /evidence=ECO:0000250 107..286 7/30 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 179..201
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 242..284 6/28 (21%)
C1_MgcRacGAP 286..339 CDD:410371 22/54 (41%)
RhoGAP_MgcRacGAP 347..540 CDD:239847 78/192 (41%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 143 1.000 Domainoid score I4632
eggNOG 1 0.900 - - E1_KOG3564
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 - 0.928771 Normalized mean entropy S4674
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0004815
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R4412
SonicParanoid 1 1.000 - - X3396
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
87.750

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