Protein Alignment AP2S1 and AP-2sigma

DIOPT Version :9

• Sequence 1: XP_011524725.1
• Gene: AP2S1 / 1175
• HGNCID: 565
• Length: 172
• Species: Homo sapiens
• Sequence 2: NP_650961.2
• Gene: AP-2sigma / 42525
• FlyBaseID: FBgn0043012
• Length: 142
• Species: Drosophila melanogaster
• Alignment Length: 155
• Identity: 135/155 - (87%)
• Similarity: 137/155 - (88%)
• Gaps: 14/155 - (9%)

Human    18 IRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEVLAISVADSLSVLQF 82
            ||||||||||||||||||||.|||||||||||||||||||||||||||||              |
  Fly     2 IRFILIQNRAGKTRLAKWYMNFDDDEKQKLIEEVHAVVTVRDAKHTNFVE--------------F 52

Human    83 RNFKIIYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEM 147
            |||||:||||||||||||||||||||.||||||||||||||||||||||||||||||||:|||||
  Fly    53 RNFKIVYRRYAGLYFCICVDVNDNNLCYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYSVVDEM 117

Human   148 FLAGEIRETSQTKVLKQLLMLQSLE 172
            |||||||||||||||||||.|.|||
  Fly   118 FLAGEIRETSQTKVLKQLLTLNSLE 142

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AP2S1	XP_011524725.1	Clat_adaptor_s	18..172	CDD:250451	133/153 (87%)
AP-2sigma	NP_650961.2	AP2_sigma	1..141	CDD:341437	132/152 (87%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158747
Domainoid	1	1.000	278	1.000	Domainoid score	I1727
eggNOG	1	0.900	-	-		E1_COG5030
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3001
Inparanoid	1	1.050	280	1.000	Inparanoid score	I2909
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53551
OrthoDB	1	1.010	-	-		D1307450at2759
OrthoFinder	1	1.000	-	-		FOG0000441
OrthoInspector	1	1.000	-	-		oto91254
orthoMCL	1	0.900	-	-		OOG6_102766
Panther	1	1.100	-	-	LDO	PTHR11753
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R63
SonicParanoid	1	1.000	-	-		X298
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800