DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gr22c and lite-1

DIOPT Version :9

Sequence 1:	NP_722732.2	Gene:	Gr22c / 117499	FlyBaseID:	FBgn0265138	Length:	383	Species:	Drosophila melanogaster
Sequence 2:	NP_509043.3	Gene:	lite-1 / 180894	WormBaseID:	WBGene00001803	Length:	439	Species:	Caenorhabditis elegans

Alignment Length:	440	Identity:	92/440 - (20%)
Similarity:	164/440 - (37%)	Gaps:	114/440 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LQSRLCWIILKATLYSSWF----LGVFPYRFDSRNGQLKRSRFLLF--YG----LILNFFLLLKM 62
            |.||..|.|...|||..::    ||:        |..::.:..|||  |.    .:|.|..|.|.
Worm    35 LSSRNKWAICDRTLYPIYYLLLILGL--------NQSIRPNNSLLFRIYSWLVFCLLLFTTLRKF 91

  Fly    63 ----VCSGGQKLGIPEAFAR--------NSVLENTHYTTGMLAVFSCVVIHFLNFWGSTRVQDLA 115
                |...|.:..:.|.||.        |:::    ..:|:||......:      |:.|::.|
Worm    92 NQVGVRPNGTRENLQEFFANPRSMITLCNALI----MLSGLLASLQLYTL------GAKRLKPL- 145

  Fly   116 NELLVLEYQQFASLN-ETKCPKFNSFVIQKWLSVIGLLLS-------------YLSIAYGLPGNN 166
             ::|.    || ||| .||..:...|:|..:|:|...||:             |:....|.|  |
Worm   146 -KILC----QF-SLNVRTKQAERRQFMINTFLAVFSGLLALTMAATYAMSKWGYILYIVGTP--N 202

  Fly   167 FSVE---MVLINSLVQFSFNCNIMHYYIGVLLIYRYLWLINGQLL----EMVTNLKLDCSVDSSR 224
            ...|   .||::|...|.....|...   .:|.|::..:|...:.    |||...:.:|.:..|.
Worm   203 LDTETIFCVLLDSYALFVSRAAISAL---AILFYQHCSVIRRSIKHLINEMVPAEQDECPLPESS 264

  Fly   225 IRKYLSL---YRRLLELKGYM------VATYEYHMTL-----VLTTGLA------SNFLAIYSWI 269
            ::|....   |:|:...|..:      |..|.|.:.:     ::..|::      |..::|..||
Worm   265 LQKIHDCQISYQRIFNGKAVIEEYYSFVLFYSYGVCIPIFCFLMFVGMSAQSICWSEVVSIVIWI 329

  Fly   270 VLDISMNINFIYLLIFPLFLLVNVWNLWLSIAASDLAENAGKSTQTVLKLFADL--EVKDIELER 332
            |..|      :.||:|             |:.|..:.|:..:...:..:::.:.  |.:|:.:..
Worm   330 VNAI------LVLLLF-------------SLPAFMINEDGDRLVASSFRMYHETFHEERDLTVLS 375

  Fly   333 SVNEFALLCGHCQFNFHVCGLFTINYKMGFQMIITSFLYLIYMIQFDFMN 382
            .:..|.......:.....|..|.::..:...:......|.:.:.:||..|
Worm   376 QMTFFTFQIHSTKLTLSACNYFYMDRSILLSLFSAILTYFLILWEFDIKN 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gr22c	NP_722732.2	7tm_7	17..382	CDD:285581	86/429 (20%)
lite-1	NP_509043.3	7tm_7	75..425	CDD:285581	77/390 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159986
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21143
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030