DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gr28b and Gr33a

DIOPT Version :9

Sequence 1:	NP_995642.1	Gene:	Gr28b / 117496	FlyBaseID:	FBgn0045495	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_525102.4	Gene:	Gr33a / 34641	FlyBaseID:	FBgn0032416	Length:	475	Species:	Drosophila melanogaster

Alignment Length:	503	Identity:	98/503 - (19%)
Similarity:	185/503 - (36%)	Gaps:	159/503 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 CLRPVFHV--------TYIHGLTSFYISCDTKTGKKAIKKTIFGYINGIMHIAMFVF--AYSLTI 98
            |:.|:|:|        ::|.|| ....||::..   .:...:|      ||:..|::  ...|::
  Fly    34 CIVPIFYVACYLLINLSHIIGL-CLLDSCNSVC---KLSSHLF------MHLGAFLYLTITLLSL 88

  Fly    99 YNNCESVASYFFRSRITYFGDLMQIVSGFIGVTVIYLTAFVPNHRLERCLQKFHTMDVQLQTVGV 163
            |...|     ||:.......|:..::                    ::| |:...|| :::...|
  Fly    89 YRRKE-----FFQQFDARLNDIDAVI--------------------QKC-QRVAEMD-KVKVTAV 126

  Fly   164 KIMYSKVLRFSYMVLISMFLVNVLFTGGTFSVLYSSEVAPTMALHFTFLIQHTVIAIAIALFSCF 228
            |  :|....|:::.|..:|         ||::.|.     ..:|:.||    ..:|....:.|.|
  Fly   127 K--HSVAYHFTWLFLFCVF---------TFALYYD-----VRSLYLTF----GNLAFIPFMVSSF 171

  Fly   229 TYL---------------VEMRLVMVNKVLKNLAHQ----------WDTRS-----LKAVN---- 259
            .||               :..|...:|.:|:.:..:          :|..|     .|.|.
  Fly   172 PYLAGSIIQGEFIYHVSVISQRFEQINMLLEKINQEARHRHAPLTVFDIESEGKKERKTVTPITV 236

  Fly   260 -------------------QKQRSLQCLDSFSMYTIVTKDPAEI------------------IQE 287
                               ::|...|..|...:.|...:|..:.                  :.:
  Fly   237 MDGRTTTGFGNENKFAGEMKRQEGQQKNDDDDLDTSNDEDEDDFDYDNATIAENTGNTSEANLPD 301

  Fly   288 SMEIHHLICEAAATANKYFTYQLLTIISIAFLIIVFDAYYVLET----LLGKSKRESKFKTVEFV 348
            ..::|..|...:...|..|..|.:..::..|::.:|..:  |||    ::|...|...:.|..:|
  Fly   302 LFKLHDKILALSVITNGEFGPQCVPYMAACFVVSIFGIF--LETKVNFIVGGKSRLLDYMTYLYV 364

  Fly   349 TF-FSCQMILYLIAIISIVEGSNRAIKKSEKTGGIVHSLLNKTKSAEVK-----EKLQQFSMQLM 407
            .: |:..|:.|::..:..     .|...|:::..|||.::.|..:..:.     .|::.|::|.:
  Fly   365 IWSFTTMMVAYIVLRLCC-----NANNHSKQSAMIVHEIMQKKPAFMLSNDLFYNKMKSFTLQFL 424

  Fly   408 HLK--INFTAAGLFNIDRTLYFTISGALTTYLIILLQF--TSNSPNNG 451
            |.:  ..|...|||.:|.|..|:...|.|:|||:||||  |:...|.|
  Fly   425 HWEGFFQFNGVGLFALDYTFIFSTVSAATSYLIVLLQFDMTAILRNEG 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gr28b	NP_995642.1	7tm_7	45..443	CDD:285581	92/490 (19%)
Gr33a	NP_525102.4	7tm_7	<289..465	CDD:303125	43/182 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR21143
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010