DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gr93b and Gr66a

DIOPT Version :9

Sequence 1:	NP_732664.2	Gene:	Gr93b / 117472	FlyBaseID:	FBgn0045470	Length:	395	Species:	Drosophila melanogaster
Sequence 2:	NP_523971.3	Gene:	Gr66a / 38935	FlyBaseID:	FBgn0035870	Length:	527	Species:	Drosophila melanogaster

Alignment Length:	487	Identity:	93/487 - (19%)
Similarity:	175/487 - (35%)	Gaps:	141/487 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 FLYGTFFGVITFRIER-KDSQLVAINRRG--YLWICLVIRLLASCFYGYSYDAWSGQYEDMYLRA 89
            |......|::...:|: :...|:..:|.|  |:...|::.::......||:    |: ||..|:|
  Fly    19 FFISKIAGILPQDLEKFRSRNLLEKSRNGMIYMLSTLILYVVLYNILIYSF----GE-EDRSLKA 78

  Fly    90 ------FFGFRLIGCLICSVIILVM----------QFWFGE--ELINLVNRFLQLFRRMQSLTNS 136
                  |    :||..:..:.:::|          |...||  |.|.||:.  :|::....:.||
  Fly    79 SQSTLTF----VIGLFLTYIGLIMMVSDQLTALRNQGRIGELYERIRLVDE--RLYKEGCVMDNS 137

  Fly   137 PKNRFGDRAEFLLMFSKVFSLLFVFMAFRLML--SPWF-LLTLVCDLYTSVGTGMITHLCFVGYL 198
               ..|.|...:|:.:.:|.|..:...:..::  |.|. ||.:|..:.|.:.|  :..:.|...|
  Fly   138 ---TIGRRIRIMLIMTVIFELSILVSTYVKLVDYSQWMSLLWIVSAIPTFINT--LDKIWFAVSL 197

  Fly   199 ------------------------------------------------SIGVLYRDLNNYVDCQL 215
                                                            ::..||::|.......:
  Fly   198 YALKERFEAINATLEELVDTHEKHKLWLRGNQEVPPPLDSSQPPQYDSNLEYLYKELGGMDIGSI 262

  Fly   216 RAQLRSLNGEN---------NSF--------RNNPQP-----------------TRQAISNLDKC 246
            .....|.:|:|         |||        |..|.|                 ..:.::||  |
  Fly   263 GKSSVSGSGKNKVAPVAHSMNSFGEAIDAASRKPPPPPLATNMVHESELGNAAKVEEKLNNL--C 325

  Fly   247 LYLYDEIHQVSRSFQQLFDLPLFLSLAQSLLAMSMVSYHAILRRQYSF--NLWGLVIKLLIDVVL 309
             .::|||.::.::..:|:..|:...:|...|..:...|......||..  :|:.......|.|::
  Fly   326 -QVHDEICEIGKALNELWSYPILSLMAYGFLIFTAQLYFLYCATQYQSIPSLFRSAKNPFITVIV 389

  Fly   310 LTMS-------VHSAVNGSRLIRRLSFE----NFYVTDSQSYHQKLELFLGRLQHQELRVFPLGL 363
            |:.:       ::.:...|:..:|....    .....|:..|.....|.|..|.| .:.....|.
  Fly   390 LSYTSGKCVYLIYLSWKTSQASKRTGISLHKCGVVADDNLLYEIVNHLSLKLLNH-SVDFSACGF 453

  Fly   364 FEVSNELTLFFLSAMVT-YLVFLVQYGMQSQQ 394
            |.:..| ||:.:|..:| ||:.|:|:.:.:||
  Fly   454 FTLDME-TLYGVSGGITSYLIILIQFNLAAQQ 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gr93b	NP_732664.2	7tm_7	24..391	CDD:285581	91/482 (19%)
Gr66a	NP_523971.3	7tm_7	21..478	CDD:285581	89/477 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR21143
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100