DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl11 and adgre10

DIOPT Version :9

Sequence 1:NP_731479.3 Gene:mthl11 / 117467 FlyBaseID:FBgn0045443 Length:532 Species:Drosophila melanogaster
Sequence 2:XP_021333746.1 Gene:adgre10 / 569655 ZFINID:ZDB-GENE-090313-152 Length:690 Species:Danio rerio


Alignment Length:268 Identity:60/268 - (22%)
Similarity:105/268 - (39%) Gaps:49/268 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   237 VFF--MVITIAAYLWLPKFRSLHGKCCNLYFICLAITFLLNVISLF-GIFELKTPICYLTGYAGY 298
            |||  .:::.|...|.|...::  ...|:....|:...||.:...| .:...:..:|.:.....:
Zfish   426 VFFSLALLSFALCQWSPGVNNV--ARINICISLLSAHLLLLLTQQFLSLIRPQQVLCVVIAGLLH 488

  Fly   299 FTVMATFLWL---SVISFDVWRRFAM---RKFQVFYKNKRSSFFNYNIIVWSSAGLLTCIIFLVD 357
            |..::.|:|:   :|:.|...:..:.   ||.:|.                 |.|.| |:|..|.
Zfish   489 FLFLSAFVWMFIEAVLLFICVKNLSQVSSRKKEVL-----------------SNGFL-CVIGYVV 535

  Fly   358 QFVETNLDNPYNP-AVGVFSCWI-FTNG--WSATFYFYAPLAILIILNCASFFLTTRYIYVENKQ 418
            ..:..::.....| ..|...||| ...|  ||    |..|:.:::.||...|...:.|:   |..
Zfish   536 ALIGVSVSIGMVPEGYGSEQCWIKMDKGFFWS----FLGPVCVILGLNVILFISISIYL---NSA 593

  Fly   419 NQKVLNNSEPQKLSRNHANYRIYFRLFIIMGGSWFLEIIAFICEMENMWKPLIILNDYINCSQGI 483
            .:|:  |:|..:|.:...........|:|:|..|.|...|.:    ||...::.:  .||..||.
Zfish   594 LKKL--NAEVSQLKQTKVMVFKTLGQFVILGCPWILGFFAHV----NMVVEIVFI--IINSQQGT 650

  Fly   484 IIFVATFC 491
            .||: .:|
Zfish   651 FIFL-IYC 657

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl11NP_731479.3 Methuselah_N 26..204 CDD:310923
7tmB3_Methuselah-like 236..504 CDD:320167 60/268 (22%)
TM helix 2 258..280 CDD:320167 4/21 (19%)
TM helix 3 291..318 CDD:320167 5/29 (17%)
TM helix 4 335..355 CDD:320167 5/19 (26%)
TM helix 5 383..412 CDD:320167 8/30 (27%)
TM helix 6 433..460 CDD:320167 6/26 (23%)
TM helix 7 468..493 CDD:320167 7/24 (29%)
adgre10XP_021333746.1 GPS 360..406 CDD:197639
7tm_GPCRs 413..672 CDD:333717 60/268 (22%)
TM helix 1 413..437 CDD:320095 3/10 (30%)
TM helix 2 446..467 CDD:320095 4/22 (18%)
TM helix 3 481..503 CDD:320095 3/21 (14%)
TM helix 4 527..543 CDD:320095 4/16 (25%)
TM helix 5 561..584 CDD:320095 7/26 (27%)
TM helix 6 608..631 CDD:320095 5/22 (23%)
TM helix 7 635..660 CDD:320095 8/26 (31%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4193
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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