Protein Alignment mthl11 and Adgrf2

DIOPT Version :9

• Sequence 1: NP_731479.3
• Gene: mthl11 / 117467
• FlyBaseID: FBgn0045443
• Length: 532
• Species: Drosophila melanogaster
• Sequence 2: XP_017452241.2
• Gene: Adgrf2 / 301269
• RGDID: 1306718
• Length: 654
• Species: Rattus norvegicus
• Alignment Length: 488
• Identity: 89/488 - (18%)
• Similarity: 166/488 - (34%)
• Gaps: 181/488 - (37%)

  Fly   100 GNLCSQDVYENLTYEYTLDITQLNGSVIK----KHVLNDMVVQQDLPLPCERH------YSLDAE 154
            |.:....:.||:|         :||.|:.    |.:.|..::.:.:....||.      :||::.
  Rat   287 GAILEASLLENMT---------VNGLVLSVILPKELKNISLIFEKIRKSGERKSQCVGWHSLESR 342

  Fly   155 TSTYDMWSLYENGSLFRHFDQRYLSKQEFC-LQPNPTSTGKNYSLIVAFNCIQKPSMKMAYGRFE 218
            ........:.||            |:|..| .|||...|  ::|::::.|.::.|
  Rat   343 WDRRACKMIQEN------------SRQAICRCQPNKFFT--SFSILMSPNTVESP---------- 383

  Fly   219 CVRKSRLSNASIPVKFSSVFFMVITIAAYLWLPKFRSLHGKCCNLYFICLAITFLL-NVISLFGI 282
                                  |:|...|:      .|....|:| .|||||..|: :.::
  Rat   384 ----------------------VLTYITYI------GLGISICSL-IICLAIEALVWSQVT---- 415

  Fly   283 FELKTPICYLTGYAGYFTVMATFLWLSVISFDVWRRFAMRKF-------------QVFYKNKRSS 334
               ||.|.||.      .:....:.::::..|||  |.:..|             ..|:.:
  Rat   416 ---KTEISYLR------HLCIANIAVTLLMADVW--FIVASFLSGPIVHHNGCVTATFFVH---- 465

  Fly   335 FFNYNIIVWSSA-------GLL--------TCIIF----------LVDQFVETNLDNPYNPAVGV 374
            ||..::..|..|       |:|        :|::.          ||...:...:..|....:..
  Rat   466 FFYLSVFFWMLAKALLILYGILIVFHTLPKSCLVASLFTVGYGCPLVIAVITLAVTEPGKGYLRP 530

  Fly   375 FSCWIFTNGWSATFYFYAPLAILIILNCASFFLTTRYIYVENKQNQKVLNNSEPQKLSRNHANYR 439
            .:||:..:...|...|..|...::::|    .:|...:.::.::
  Rat   531 EACWLNWDMTKALLAFVVPALAIVVVN----LITVTLVIIKTQR--------------------- 570

  Fly   440 IYFRLFIIMGGSWFLEI--IAFICEMENMWKPLIILNDYINCSQGIIIFVA--TFCNHEMFRLIR 500
                  ..:|.|.|.|:  |..||:...:..||:.|    ....||...||  :...|.:|.|
  Rat   571 ------AAVGSSMFQEVRAIVRICKNIAILTPLLGL----TWGFGIATVVAGHSLAFHIIFSL-- 623

  Fly   501 KRIQNRNITSLELTNTSRPVESE-KMADVELGK 532
                   :.:|:::..:. :||| :...||.|:
  Rat   624 -------LNALQVSPDAM-IESEWRGCAVECGR 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mthl11	NP_731479.3	Methuselah_N	26..204	CDD:310923	23/114 (20%)
		7tmB3_Methuselah-like	236..504	CDD:320167	57/310 (18%)
		TM helix 2	258..280	CDD:320167	8/22 (36%)
		TM helix 3	291..318	CDD:320167	5/26 (19%)
		TM helix 4	335..355	CDD:320167	7/44 (16%)
		TM helix 5	383..412	CDD:320167	5/28 (18%)
		TM helix 6	433..460	CDD:320167	5/28 (18%)
		TM helix 7	468..493	CDD:320167	7/26 (27%)
Adgrf2	XP_017452241.2	GPS	330..377	CDD:413374	12/60 (20%)
		7tm_GPCRs	382..628	CDD:421689	58/347 (17%)
		TM helix 1	384..409	CDD:410628	11/31 (35%)
		TM helix 2	424..446	CDD:410628	4/23 (17%)
		TM helix 3	458..485	CDD:410628	5/30 (17%)
		TM helix 4	499..519	CDD:410628	2/19 (11%)
		TM helix 5	539..568	CDD:410628	5/32 (16%)
		TM helix 6	584..610	CDD:410628	8/29 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910