DRSC/TRiP Functional Genomics Resources

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Protein Alignment mthl11 and gpr157

DIOPT Version :9

Sequence 1:NP_731479.3 Gene:mthl11 / 117467 FlyBaseID:FBgn0045443 Length:532 Species:Drosophila melanogaster
Sequence 2:NP_001124512.1 Gene:gpr157 / 100038048 XenbaseID:XB-GENE-492646 Length:323 Species:Xenopus tropicalis


Alignment Length:292 Identity:61/292 - (20%)
Similarity:110/292 - (37%) Gaps:63/292 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   241 VITIAAYLWLPKFRSLHGKCCNLYFICLAITFLLNVISLF-GI---FELKTPICYLTGYAGYFTV 301
            :|.:...||    :.|..: ..|..:.|::..||:.:|.| |:   |:..|..|...|....|:.
 Frog    32 LIIVTYILW----QDLRSR-PRLLLLFLSVADLLSALSYFYGVLRNFQDSTWDCVTQGAISTFSN 91

  Fly   302 MATFLWLSVISFDVWRRFAMRKFQVFYKNKRSSFFNYNIIVW---SSAGLLTCIIFLVDQFVETN 363
            .::|.|...:        |:..:....|:::|  |...||.|   .|.|:...|........:..
 Frog    92 TSSFFWTVAV--------AVYLYITIVKSQQS--FADQIIPWLHLISWGVPLVITLSAVCLKKIG 146

  Fly   364 LDNPYNPAVGVFSCWIFTN-------------GWSATFYFYAPLAILIILNCASFFLTTRYI--- 412
            .|..|   |.|..||:..:             .|....|...|:..::|         .::|   
 Frog   147 YDASY---VSVGWCWVKIDVEDKLLWMLLAGKVWEILAYLILPVLYILI---------KKHIGRA 199

  Fly   413 YVENKQNQKVLNNSEPQKLSRNHANYRIYF--RLFIIMGGSWFLEIIAFICEMENMWKPLII-LN 474
            :....:.:.:|..| |....|..|:.::.|  .:||.:.....:..|..:|:...:..|::: |:
 Frog   200 HAALAEYRPILATS-PVNQPRTIADKKLVFIPIIFIFLRVWSTIRFILTLCDSPAVHNPILVTLH 263

  Fly   475 DYINCSQG---IIIFVATFCNHEMFRLIRKRI 503
            ...|..||   .|:||  .|.    .:||.|:
 Frog   264 GIGNTFQGGANCIMFV--LCT----PVIRSRL 289

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mthl11NP_731479.3 Methuselah_N 26..204 CDD:310923
7tmB3_Methuselah-like 236..504 CDD:320167 61/292 (21%)
TM helix 2 258..280 CDD:320167 5/21 (24%)
TM helix 3 291..318 CDD:320167 4/26 (15%)
TM helix 4 335..355 CDD:320167 7/22 (32%)
TM helix 5 383..412 CDD:320167 4/28 (14%)
TM helix 6 433..460 CDD:320167 6/28 (21%)
TM helix 7 468..493 CDD:320167 9/28 (32%)
gpr157NP_001124512.1 7tm_GPCRs 17..>192 CDD:391938 37/177 (21%)
TM helix 1 17..39 CDD:341315 1/6 (17%)
TM helix 2 48..69 CDD:341315 6/20 (30%)
TM helix 3 81..103 CDD:341315 4/29 (14%)
TM helix 4 123..139 CDD:341315 4/15 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 49 1.000 Inparanoid score I5275
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.050

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