DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ste12DOR and csnk2b

DIOPT Version :9

Sequence 1:	NP_727747.3	Gene:	Ste12DOR / 117463	FlyBaseID:	FBgn0044817	Length:	172	Species:	Drosophila melanogaster
Sequence 2:	NP_571262.1	Gene:	csnk2b / 30428	ZFINID:	ZDB-GENE-990415-29	Length:	215	Species:	Danio rerio

Alignment Length:	174	Identity:	73/174 - (41%)
Similarity:	102/174 - (58%)	Gaps:	15/174 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSSSQNNNSSWIDWFLGIKGNQFLCRVPTDYVQDTFNQMGLE----YFSEILDVILKPVID---- 57
            ||||:  ..|||.||.|::||:|.|.|..||:||.||..||.    ::.:.||:||....|
Zfish     1 MSSSE--EVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELE 63

  Fly    58 ---SSSGLLYGDEKKWYGMIHARYIRSERGLIAMHRKYMRGDFGSCPNISCDRQNTLPVGVSAVW 119
               :.|.|:....:..||:||||||.:.||:..|..||.:||||.||.:.|:.|..||:|:|.:.
Zfish    64 DNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIP 128

  Fly   120 GKSTVKIHCPRCKSNFHPKSDT--QLDGAMFGPSFPDIFFSMLP 161
            |::.||::||:|...:.|||..  ..|||.||..||.:.|.:.|
Zfish   129 GEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHP 172

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ste12DOR	NP_727747.3	CK_II_beta	11..166	CDD:198153	68/164 (41%)
csnk2b	NP_571262.1	CK_II_beta	8..191	CDD:198153	69/165 (42%)
csnk2b	NP_571262.1	Interaction with alpha subunit. /evidence=ECO:0000250	188..193
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5041
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53662
OrthoDB	1	1.010	-	-		D1335521at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11740
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	7	6.890