Protein Alignment Irbp and KU70

DIOPT Version :9

• Sequence 1: NP_536773.1
• Gene: Irbp / 117419
• FlyBaseID: FBgn0011774
• Length: 631
• Species: Drosophila melanogaster
• Sequence 2: NP_564012.1
• Gene: KU70 / 838268
• AraportID: AT1G16970
• Length: 621
• Species: Arabidopsis thaliana
• Alignment Length: 671
• Identity: 148/671 - (22%)
• Similarity: 275/671 - (40%)
• Gaps: 108/671 - (16%)

  Fly     7 ENDVDLLSGSEDEE---DVSMKRDYHGREAILFVVDAN----LQTAGVE-------RLLEALNII 57
            |.|.|.:...|||:   |...::: ..:|.:::::||:    ..|...|       ....|::.|
plant     2 ELDPDDVFRDEDEDPENDFFQEKE-ASKEFVVYLIDASPKMFCSTCPSEEEDKQESHFHIAVSCI 65

  Fly    58 RTAFISGLLVNDKDLIGLIFANTKHSPPPLEASALDNIVMPDNCAVFLPLRQLTK--PIVEHYLE 120
            ..:..:.::....|.|.:.|.||:......:.:.:....:|:..::..|..:|.|  .::|...:
plant    66 AQSLKAHIINRSNDEIAICFFNTREKKNLQDLNGVYVFNVPERDSIDRPTARLIKEFDLIEESFD 130

  Fly   121 FMGGVETQFADVYGLAEPDGRGRFDLMIRLCIEMLEKCGKKLNNAKIAYVTDVREPHPS-----N 180
            ...|.:|      |:............:.:...:|.|...|..:.::...|:..:|..|     .
plant   131 KEIGSQT------GIVSDSRENSLYSALWVAQALLRKGSLKTADKRMFLFTNEDDPFGSMRISVK 189

  Fly   181 SNHFQAALQKASDLEGKEFEFHVIPMVD---DFDYEPFYKEFITLSRAIELDAFQVPDAQMLREI 242
            .:..:..||:|.|.:.......::|:..   .|:...|||:.|.|: :.||..| :|......|.
plant   190 EDMTRTTLQRAKDAQDLGISIELLPLSQPDKQFNITLFYKDLIGLN-SDELTEF-MPSVGQKLED 252

  Fly   243 LSDRKLKQDFLRRCLGHFSFYLGPNLSMSVQYYNYFQRRAYPRKVQILRRDNSVVRTKRVITVQK 307
            :.|:..|:...:|.....:|.:...||:.:..|... |.|.|..:..|  |::   |...:.|::
plant   253 MKDQLKKRVLAKRIAKRITFVICDGLSIELNGYALL-RPAIPGSITWL--DST---TNLPVKVER 311

  Fly   308 Q---KDDGS--QD-IEHEYQIKVTGGWYTCNVGERDLRISMDQLNRVRNLHKPQMMLLGFKHRSS 366
            .   .|.|:  || |:.....|           .:::..::::|::|:.:....:.|||||..|.
plant   312 SYICTDTGAIMQDPIQRIQPYK-----------NQNIMFTVEELSQVKRISTGHLRLLGFKPLSC 365

  Fly   367 LPEVSYIKPANFMYPDDQSIIGSKRLFRALWERCLVRDKIAICLFMCKRKSIPRYVALV---PVE 428
            |.:...:||:.|:||.|:.:|||.|.|.||....:..::.|:..:  ...:.||.||||   .:|
plant   366 LKDYHNLKPSTFLYPSDKEVIGSTRAFIALHRSMIQLERFAVAFY--GGTTPPRLVALVAQDEIE 428

  Fly   429 APDNGEDKNYRSLLCGDGFKIVYLPEAKHIRHLDLQDWNNTENT----ADEQKVEFFQKIIKKLR 489
            : |.|:.:       ..|..::|||.|..||  |:.:.::....    |.:.:::....::::|.
plant   429 S-DGGQVE-------PPGINMIYLPYANDIR--DIDELHSKPGVAAPRASDDQLKKASALMRRLE 483

  Fly   490 V-DYQPNLINDPSLDALQANLLALSLDFSTDTKGLDNLLDTSQQDKR------IEKLL------- 540
            : |:......:|:|....|.|.|::||.:...:..|..|...:...|      ||:..
plant   484 LKDFSVCQFANPALQRHYAILQAIALDENELRETRDETLPDEEGMNRPAVVKAIEQFKQSIYGDD 548

  Fly   541 PDYEMFAPEAEPHKKRAAKSTTAGASGPKMAKIDDDQLKEFEFVKSLNKDEALTSCTAAQLHFIL 605
            ||.|..:...|..|||.|.....|       |.|..:|.:...:|.|...|..|..||..|..
plant   549 PDEESDSGAKEKSKKRKAGDADDG-------KYDYIELAKTGKLKDLTVVELKTYLTANNLLV-- 604

  Fly   606 QHHFDVTMPKSSKKAKLVAKI 626
                      |.||..|:.:|
plant   605 ----------SGKKEVLINRI 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irbp	NP_536773.1	Ku_N	33..256	CDD:367627	43/243 (18%)
		KU70	255..546	CDD:238407	76/317 (24%)
		HeH	593..624	CDD:338564	8/30 (27%)
KU70	NP_564012.1	ku70	24..619	CDD:273151	141/649 (22%)
		KU70	265..544	CDD:238407	73/307 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	64	1.000	Domainoid score	I3688
eggNOG	1	0.900	-	-		E1_KOG2327
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H37483
Inparanoid	1	1.050	82	1.000	Inparanoid score	I2360
OMA	1	1.010	-	-		QHG55383
OrthoDB	1	1.010	-	-		D402798at2759
OrthoFinder	1	1.000	-	-		FOG0005016
OrthoInspector	1	1.000	-	-		oto3639
orthoMCL	1	0.900	-	-		OOG6_102426
Panther	1	1.100	-	-	LDO	PTHR12604
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.840