Protein Alignment Irbp and Xrcc6

DIOPT Version :9

• Sequence 1: NP_536773.1
• Gene: Irbp / 117419
• FlyBaseID: FBgn0011774
• Length: 631
• Species: Drosophila melanogaster
• Sequence 2: NP_620780.2
• Gene: Xrcc6 / 25019
• RGDID: 2643
• Length: 608
• Species: Rattus norvegicus
• Alignment Length: 662
• Identity: 166/662 - (25%)
• Similarity: 305/662 - (46%)
• Gaps: 86/662 - (12%)

  Fly     1 MSTWNPENDVDLLSGSEDEE-----DVSMKRDYHGREAILFVVDAN---LQTAGVERLLE---AL 54
            ||.|......:   |.|:||     |.:.:..|.||::::|:|||:   .::.|.:.|..   ::
  Rat     1 MSEWESYYKTE---GEEEEEEEQSPDTNGEYKYSGRDSLIFLVDASRAMFESQGEDELTPFDMSI 62

  Fly    55 NIIRTAFISGLLVNDKDLIGLIFANTKHSPPPLEASALDNIVMPDNCAVFLPLRQLTKPIVEHYL 119
            ..|::.:.|.::.:|:||:.::|..|:..         .|.|   |......|:.|..|..:..|
  Rat    63 QCIQSVYTSKIISSDRDLLAVVFYGTEKD---------KNSV---NFKSIYVLQDLDNPGAKRVL 115

  Fly   120 E---FMGGV-ETQFADV------YGLAEPDGRGRFDLMIRLCIEMLEKCGKKLNNAKIAYVTDVR 174
            |   |.|.. :..|.|.      |.|:|         ::.:|..:......|:::.:|...|:..
  Rat   116 ELDRFKGQQGKKHFRDTIGHGSDYSLSE---------VLWVCANLFSDVQFKMSHKRIMLFTNED 171

  Fly   175 EPHPSNSNHFQAALQKASDLE--GKEFEFHVIPMVDDFDYEPFYKEFITLSRAIELDAFQVPDAQ 237
            :||.::|.....|..|||||.  |...:...:.....||...||::.|:::...:| .....::.
  Rat   172 DPHGNDSAKASRARTKASDLRDTGIFLDLMHLKKRGGFDVSLFYRDIISIAEDEDL-GVHFEESS 235

  Fly   238 MLREILSDRKLK-QDFLRRCLGHFSFYLGPNLSMSVQYYNYFQRRAYPRKVQILRRDNSVVRTK- 300
            .|.::|  ||:: ::..:|.|....|.||.::::.|..||..|:...|..|::.|..|..|:||
  Rat   236 KLEDLL--RKVRAKETKKRVLSRLKFKLGKDVALMVGVYNLVQKANKPFPVRLYRETNEPVKTKT 298

  Fly   301 RVITVQKQKDDGSQDIEHEYQIKVTGGWYTCNVGERDLRISMDQLNRVRNLHKPQMMLLGFKHRS 365
            |...|    :.||..:..:.:..:|       .|.|.:.:..::...::...:|.::|:|||...
  Rat   299 RTFNV----NTGSLLLPSDTKRSLT-------FGTRQIVLEKEETEELKRFDEPGLILMGFKPMV 352

  Fly   366 SLPEVSYIKPANFMYPDDQSIIGSKRLFRALWERCLVRDKIAICLFMCKRKSIPRYVALVPVEAP 430
            .|....|::|:.|:||::..:.||..||.||..:|:.::.||:|.:..::...|.:|||||.|
  Rat   353 MLKNHHYLRPSLFLYPEESLVNGSSTLFSALLTKCVEKEVIAVCRYTARKNVSPYFVALVPQE-- 415

  Fly   431 DNGEDKNYRSLLCGDGFKIVYLPEAKHIRHLDLQDWNNTENT-ADEQKVEFFQKIIKKLRVDYQP 494
            :..:|:|.:  :...||::|:||.|...|.:..     ||.. |:.::::..:.|::|||..|:.
  Rat   416 EELDDQNIQ--VTPAGFQLVFLPYADDKRKVPF-----TEKVMANPEQIDKMKAIVQKLRFTYRS 473

  Fly   495 NLINDPSLDALQANLLALSLDFSTDTKGLDNLLDTSQQ-DKRIEKLLPDYE--MFAPEAEPHKKR 556
            :...:|.|.....||.||:||.....:.:|..|...:. .||:..|..:::  ::.|...|..|.
  Rat   474 DSFENPVLQQHFRNLEALALDMMESEQVVDLTLPKVEAIKKRLGSLADEFKELVYPPGYNPEGKI 538

  Fly   557 AAKSTTAGASGPKMAKID--DDQLKEFEFVKSLNKDEALTSCTAAQLHFILQHHFDVTMPKSSKK 619
            |.:......|..|..|::  :::||:. |.|.     .|...|...|..|.:.:...:.||  |:
  Rat   539 AKRKADNEGSASKKPKVELSEEELKDL-FAKG-----TLGKLTVPALRDICKAYGLKSGPK--KQ 595

  Fly   620 AKLVAKIEELHK 631
            ..|.|....|.|
  Rat   596 ELLEALSRHLEK 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irbp	NP_536773.1	Ku_N	33..256	CDD:367627	52/241 (22%)
		KU70	255..546	CDD:238407	81/295 (27%)
		HeH	593..624	CDD:338564	8/30 (27%)
Xrcc6	NP_620780.2	ku70	22..606	CDD:273151	157/635 (25%)
		vWA_ku	33..247	CDD:238735	53/237 (22%)
		KU70	252..527	CDD:238407	81/294 (28%)
		SAP	571..605	CDD:280251	9/35 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341465
Domainoid	1	1.000	87	1.000	Domainoid score	I7866
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37483
Inparanoid	1	1.050	162	1.000	Inparanoid score	I4114
OMA	1	1.010	-	-		QHG55383
OrthoDB	1	1.010	-	-		D402798at2759
OrthoFinder	1	1.000	-	-		FOG0005016
OrthoInspector	1	1.000	-	-		oto97701
orthoMCL	1	0.900	-	-		OOG6_102426
Panther	1	1.100	-	-	LDO	PTHR12604
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.910