Protein Alignment Tsp68C and CD81

DIOPT Version :10

• Sequence 1: NP_729926.1
• Gene: Tsp68C / 117407
• FlyBaseID: FBgn0043550
• Length: 362
• Species: Drosophila melanogaster
• Sequence 2: XP_054226604.1
• Gene: CD81 / 975
• HGNCID: 1701
• Length: 335
• Species: Homo sapiens
• Alignment Length: 262
• Identity: 50/262 - (19%)
• Similarity: 99/262 - (37%)
• Gaps: 76/262 - (29%)

  Fly    22 GLLLVVSGLYIFSDNKRILLSRLLAASSDRLSSLPQPLLFYIALGVAIA-GFVATLAAVVGFWAS 85
            |::|.|: |::..|.:...|..|      .|...|.|..||:.:.:.|| |.|......:|.:.:
Human   125 GVILGVA-LWLRHDPQTTNLLYL------ELGDKPAPNTFYVGIYILIAVGAVMMFVGFLGCYGA 182

  Fly    86 CLHTYCFLTIYFLSVVVLLLTESVLCLAITLWPHCLGISLDETQMVRSLQSNYGVPGQE------ 144
            ...:.|.|..:|..:|:|...|    :|..:|..     :::.|:.:.::..|....|:
Human   183 IQESQCLLGTFFTCLVILFACE----VAAGIWGF-----VNKDQIAKDVKQFYDQALQQAVVDDD 238

  Fly   145 ---------QFTNALDLAQVRFGCCGMRSSLDYDTSLWRLQGYGQRNWPVPLSCCFLKNAGHSMA 200
                     .|...||       |||..:.....||:                   |||
Human   239 ANNAKAVVKTFHETLD-------CCGSSTLTALTTSV-------------------LKN------ 271

  Fly   201 YLDPKPANESMCQSLERLSYERERHTESCLPHLDNWYR-EQYSIFLGASLILAMIEFCVLLAIIM 264
              :..|:..::..:|.:         |.|...:|:.:. :.|.|.:.|.::..::.|.::|::::
Human   272 --NLCPSGSNIISNLFK---------EDCHQKIDDLFSGKLYLIGIAAIVVAVIMIFEMILSMVL 325

  Fly   265 SC 266
            .|
Human   326 CC 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp68C	NP_729926.1	Tetraspanin	8..>161	CDD:459767	32/154 (21%)
		tetraspanin_LEL	117..241	CDD:239401	20/139 (14%)
CD81	XP_054226604.1	Tetraspanin	122..327	CDD:459767	49/260 (19%)