Protein Alignment Tsp68C and CD53

DIOPT Version :10

• Sequence 1: NP_729926.1
• Gene: Tsp68C / 117407
• FlyBaseID: FBgn0043550
• Length: 362
• Species: Drosophila melanogaster
• Sequence 2: NP_000551.1
• Gene: CD53 / 963
• HGNCID: 1686
• Length: 219
• Species: Homo sapiens
• Alignment Length: 278
• Identity: 53/278 - (19%)
• Similarity: 95/278 - (34%)
• Gaps: 76/278 - (27%)

  Fly     8 KFVLNLCNFLFLICGLLLVVSGLYIFSDNKRILLSRLLAASSDRLSSLPQPLLFYIALG--VAIA 70
            |:||...|.||.|||..::..|:|:...|...:|          ..:||.     :.||  ..|.
Human    10 KYVLFFFNLLFWICGCCILGFGIYLLIHNNFGVL----------FHNLPS-----LTLGNVFVIV 59

  Fly    71 GFVATLAAVVGFWASCLHTYCFLTIYFLSVVVLLLTESVLCLAITLWPHCLG--ISLDETQMVRS 133
            |.:..:.|.:|...|.....|.|..:|:.::::||.|..|.:.:.::...|.  ::...|..:..
Human    60 GSIIMVVAFLGCMGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLNEYVAKGLTDSIHR 124

  Fly   134 LQSNYGVPGQEQFTNALDLAQVRFGCCGMRSSLDYDTSLWRLQGYGQRNWPVPLSCCFLKNAGHS 198
            ..|:.....      |.|..|....|||:..:.|:.:.             .|.||
Human   125 YHSDNSTKA------AWDSIQSFLQCCGINGTSDWTSG-------------PPASC--------- 161

  Fly   199 MAYLDPKPANESMCQSLERLSYERERHTESCLPHLDNWYREQYSIFLGASLILAMIEFCVLLAII 263
                   |:               :|..|.|......|:...:       |.:.:|..||.:..:
Human   162 -------PS---------------DRKVEGCYAKARLWFHSNF-------LYIGIITICVCVIEV 197

  Fly   264 MSCTGLASQRARLKKPVQ 281
            :..:...:...::.|..|
Human   198 LGMSFALTLNCQIDKTSQ 215

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp68C	NP_729926.1	Tetraspanin	8..>161	CDD:459767	36/156 (23%)
		tetraspanin_LEL	117..241	CDD:239401	18/125 (14%)
CD53	NP_000551.1	Tetraspanin	9..208	CDD:459767	51/269 (19%)
		CD53_like_LEL	104..186	CDD:239417	19/138 (14%)