Protein Alignment Tsp68C and TSPAN18

DIOPT Version :10

• Sequence 1: NP_729926.1
• Gene: Tsp68C / 117407
• FlyBaseID: FBgn0043550
• Length: 362
• Species: Drosophila melanogaster
• Sequence 2: XP_005253274.1
• Gene: TSPAN18 / 90139
• HGNCID: 20660
• Length: 258
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 62/282 - (21%)
• Similarity: 112/282 - (39%)
• Gaps: 63/282 - (22%)

  Fly     3 CCFNYKFVLNLCNFLFLICGLLLVVSGLYIFSDNKRILLSRLLAASSDRLSSLPQPLLF---YIA 64
            |....|:::.:.||...:.|..|:..|:::..|...  ...::||:         |||.   ||.
Human    15 CLSCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTG--FREIVAAN---------PLLLTGAYIL 68

  Fly    65 LGVAIAGFVATLAAVVGFWASC---LHTYCFLTIYFLSVVVLLLTESVLCLAITLWPHCLGISLD 126
            |  |:.|    |..::||...|   ....|.|..:||.::::.|.|    |:..:.......:|.
Human    69 L--AMGG----LLFLLGFLGCCGAVRENKCLLLFFFLFILIIFLAE----LSAAILAFIFRENLT 123

  Fly   127 ETQMVRSLQSNY-GVPGQEQFTNALDLAQVRFGCCGMRSSLDYD-TSLWRLQGYGQRNWPVPLSC 189
            .....:.|..:| |....:.|:...:...:.|||||:....|:. .|::||.......  ||.:|
Human   124 REFFTKELTKHYQGNNDTDVFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEE--VPEAC 186

  Fly   190 CFLKNAGHSMAYLDPKPANESMCQSLERLSYERER---------HTESCLPHLDNWYREQYSIFL 245
            |          ..:|        ||.:.:...||.         :.:.|...:.|.: |.| ::|
Human   187 C----------RREP--------QSRDGVLLSREECLLGRSLFLNKQGCYTVILNTF-ETY-VYL 231

  Fly   246 GASL---ILAMIEFCVLLAIIM 264
            ..:|   :||:..|.::.|:.:
Human   232 AGALAIGVLAIELFAMIFAMCL 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp68C	NP_729926.1	Tetraspanin	8..>161	CDD:459767	36/159 (23%)
		tetraspanin_LEL	117..241	CDD:239401	26/134 (19%)
TSPAN18	XP_005253274.1	Tetraspanin	20..255	CDD:459767	61/277 (22%)
		uroplakin_I_like_LEL	115..228	CDD:239409	26/133 (20%)