Protein Alignment Tsp68C and UPK1B

DIOPT Version :10

• Sequence 1: NP_729926.1
• Gene: Tsp68C / 117407
• FlyBaseID: FBgn0043550
• Length: 362
• Species: Drosophila melanogaster
• Sequence 2: NP_008883.2
• Gene: UPK1B / 7348
• HGNCID: 12578
• Length: 260
• Species: Homo sapiens
• Alignment Length: 233
• Identity: 50/233 - (21%)
• Similarity: 86/233 - (36%)
• Gaps: 31/233 - (13%)

  Fly     4 CFNYKFVLNLCNFLFLICGLLLVVSGLYIFSDNKRILLSRLLAASSDRLSSLPQPLLFYIALGVA 68
            ||....:..  |.:...||:.|....::..|| :..|...|.|..:|.:....     :|.:.|.
Human    10 CFQGLLIFG--NVIIGCCGIALTAECIFFVSD-QHSLYPLLEATDNDDIYGAA-----WIGIFVG 66

  Fly    69 IAGFVATLAAVVGFWASCLHTYCFLTIYFLSVVVLLLTESVLCLAITLWPHCLGISLDETQMVRS 133
            |..|..::..:||...|   :...|..||:.:.::...|...|:...........:|...||:..
Human    67 ICLFCLSVLGIVGIMKS---SRKILLAYFILMFIVYAFEVASCITAATQQDFFTPNLFLKQMLER 128

  Fly   134 LQSNYGVPGQEQF-----TNALDLAQVRFGCCGMRSSLDYD--TSLWRLQGYGQRNWPVPLSCCF 191
            .|:|......:|:     |...|...::..|||:....|:.  ||.:|.:. ...::|.|..||.
Human   129 YQNNSPPNNDDQWKNNGVTKTWDRLMLQDNCCGVNGPSDWQKYTSAFRTEN-NDADYPWPRQCCV 192

  Fly   192 LKNAGHSMAYLDPKPANESMCQSLERLSYERERHTESC 229
            :.|.        .:|.|...|    :|......|.:.|
Human   193 MNNL--------KEPLNLEAC----KLGVPGFYHNQGC 218

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp68C	NP_729926.1	Tetraspanin	8..>161	CDD:459767	31/157 (20%)
		tetraspanin_LEL	117..241	CDD:239401	26/120 (22%)
UPK1B	NP_008883.2	Tetraspanin	14..>161	CDD:459767	31/157 (20%)
		uroplakin_I_like_LEL	118..230	CDD:239409	26/114 (23%)