Protein Alignment Tsp68C and Tspan17

DIOPT Version :10

• Sequence 1: NP_729926.1
• Gene: Tsp68C / 117407
• FlyBaseID: FBgn0043550
• Length: 362
• Species: Drosophila melanogaster
• Sequence 2: XP_006253692.1
• Gene: Tspan17 / 306771
• RGDID: 1311167
• Length: 281
• Species: Rattus norvegicus
• Alignment Length: 282
• Identity: 60/282 - (21%)
• Similarity: 112/282 - (39%)
• Gaps: 68/282 - (24%)

  Fly     1 MACCFNYKFVLNLCNFLFLICGLLLVVSGLYIFSDNKRILLSRLLAASSDRLSSLPQPLLFYIAL 65
            :.||..| |:... |.:|.:.|.|.:..||:.:.: |.:|.:  ::..:| |..| .|:..::.:
  Rat    13 VGCCGKY-FLFGF-NIVFWVLGALFLAIGLWAWGE-KGVLSN--ISGLTD-LGGL-DPVWLFVVI 70

  Fly    66 GVAIAGFVATLAAVVGFWASCL-----HTYC--FLTIYFLSVVVLLLTESVLCLAITLWPHCLGI 123
            |        .:.:|:|| |.|:     :|:.  |.:::...:..|.|...:|......|..
  Rat    71 G--------GIMSVLGF-AGCIGALRENTFLLKFFSVFLGLIFFLELAAGILAFVFKDWIR---- 122

  Fly   124 SLDETQM-----VRSLQSNYGVPGQEQFTNALDLAQVRFGCCGMRSSLDYDTSLWRLQGY----- 178
              |:..:     |::.:.:.      ...|.:|.||..:.|||.|...|     |.|..|
  Rat   123 --DQLNLFINNNVKAYRDDI------DLQNLIDFAQEYWSCCGARGPND-----WNLNIYFNCTD 174

  Fly   179 ---GQRNWPVPLSCCFLKNAGHSMAYLDP-KPANESMCQSLERLSYERER----HTESCLPHLDN 235
               .:....||.|||          ..|| :....:.|....||..|.|:    :|:.|:...:.
  Rat   175 LNPSRERCGVPFSCC----------VRDPAEDVLNTQCGYDIRLKLELEQQGSIYTKGCVGQFEK 229

  Fly   236 WYREQYSIFLGASLILAMIEFC 257
            |.::...:..|..:.:|:::.|
  Rat   230 WLQDNLIVVAGVLVAIALLQIC 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp68C	NP_729926.1	Tetraspanin	8..>161	CDD:459767	32/164 (20%)
		tetraspanin_LEL	117..241	CDD:239401	30/141 (21%)
Tspan17	XP_006253692.1	Tetraspanin	18..260	CDD:459767	58/277 (21%)
		TM4SF9_like_LEL	115..235	CDD:239412	30/146 (21%)