Protein Alignment Tsp68C and Tspan12

DIOPT Version :10

• Sequence 1: NP_729926.1
• Gene: Tsp68C / 117407
• FlyBaseID: FBgn0043550
• Length: 362
• Species: Drosophila melanogaster
• Sequence 2: NP_766595.1
• Gene: Tspan12 / 269831
• MGIID: 1889818
• Length: 305
• Species: Mus musculus
• Alignment Length: 314
• Identity: 70/314 - (22%)
• Similarity: 129/314 - (41%)
• Gaps: 62/314 - (19%)

  Fly     9 FVLNLCNFLFLICGLLLVVSGLYIFSDNKRILLSRLLAASSDRLSSLP--QPLLFYIALGVAIAG 71
            :.|||..:|..| .:|.|.:.:..:.:|...|.:......:..|:..|  .|::..:...:.|.|
Mouse    15 YALNLLFWLMSI-SVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYFPVVHPVMIAVCCFLIIVG 78

  Fly    72 FVATLAAVVGFWASCLHTYCFLTIYFLSVVVLLLTESVLCLAITLWPH----CLGISLDETQMVR 132
                   ::|:..:.......|..||.:::|:...|    ||..:|.:    .:.:...:...::
Mouse    79 -------MLGYCGTVKRNLLLLAWYFGTLLVIFCVE----LACGVWTYEQEVMVPVQWSDMVTLK 132

  Fly   133 SLQSNYGVPGQEQFTNALDLAQVRFGCCGMRSSLDYDTSLWRLQGYGQRNWPVPLSCCFLKNAGH 197
            :..:|||:|.....|:|.:..|..|.|||:....|:      |: ..:.:|| |.|||..:..|.
Mouse   133 ARMTNYGLPRYRWLTHAWNYFQREFKCCGVVYFTDW------LE-MTEMDWP-PDSCCVREFPGC 189

  Fly   198 SMAYLDPKPANESMCQSLERLSYERERHTESCLPHLDNWYR--EQYSI--FLGASLILAMIEFCV 258
            |      |.|::      |.||   :.:.|.|...:.::.|  :|..:  |||.|:.:..|
Mouse   190 S------KQAHQ------EDLS---DLYQEGCGKKMYSFLRGTKQLQVLRFLGISIGVTQI---- 235

  Fly   259 LLAIIMSCTGL-----------ASQRARLKKPV-QEMRTQKVKSRQTLIENIYE 300
             ||:|::.|.|           ..|...||... |.:....|:..:..:..|:|
Mouse   236 -LAMILTITLLWALYYDRREPGTDQMLSLKNDTSQHLSCHSVELLKPSLSRIFE 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp68C	NP_729926.1	Tetraspanin	8..>161	CDD:459767	32/157 (20%)
		tetraspanin_LEL	117..241	CDD:239401	30/129 (23%)
Tspan12	NP_766595.1	Tetraspanin	10..246	CDD:459767	62/270 (23%)
		TM4SF12_like_LEL	116..218	CDD:239410	29/124 (23%)