Protein Alignment Tsp68C and TSPAN17

DIOPT Version :10

• Sequence 1: NP_729926.1
• Gene: Tsp68C / 117407
• FlyBaseID: FBgn0043550
• Length: 362
• Species: Drosophila melanogaster
• Sequence 2: NP_001353420.1
• Gene: TSPAN17 / 26262
• HGNCID: 13594
• Length: 355
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 65/281 - (23%)
• Similarity: 108/281 - (38%)
• Gaps: 70/281 - (24%)

  Fly     1 MACCFNYKFVLNLCNFLFLICGLLLVVSGLYIFSDNKRILLSRLLAASSDRLSSLPQPLLFYIAL 65
            :.||..| |:... |.:|.:.|.|.:..||:.:.: |.:|.:  ::|.:| |..|....||.:..
Human    13 VGCCGKY-FLFGF-NIVFWVLGALFLAIGLWAWGE-KGVLSN--ISALTD-LGGLDPVWLFVVVG 71

  Fly    66 GVAIAGFVATLAAVVGFWASCL-----HTYC--FLTIYFLSVVVLLLTESVLCLAITLWPHCLGI 123
            ||         .:|:|| |.|:     :|:.  |.:::...:..|.|...:|......|
Human    72 GV---------MSVLGF-AGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDW------ 120

  Fly   124 SLDETQMVR---SLQSNYGVPGQE---QFTNALDLAQVRFGCCGMRSSLDYDTSLWRLQGY---- 178
                   :|   :|..|..|....   ...|.:|.||..:.|||.|...|     |.|..|
Human   121 -------IRDQLNLFINNNVKAYRDDIDLQNLIDFAQEYWSCCGARGPND-----WNLNIYFNCT 173

  Fly   179 ----GQRNWPVPLSCCFLKNAGHSMAYLDP-KPANESMCQSLERLSYERER----HTESCLPHLD 234
                .:....||.|||          ..|| :....:.|....||..|.|:    ||:.|:...:
Human   174 DLNPSRERCGVPFSCC----------VRDPAEDVLNTQCGYDVRLKLELEQQGFIHTKGCVGQFE 228

  Fly   235 NWYREQYSIFLGASLILAMIE 255
            .|.::...:..|..:.:|:::
Human   229 KWLQDNLIVVAGVFMGIALLQ 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp68C	NP_729926.1	Tetraspanin	8..>161	CDD:459767	37/165 (22%)
		tetraspanin_LEL	117..241	CDD:239401	33/142 (23%)
TSPAN17	NP_001353420.1	Tetraspanin	18..>157	CDD:459767	38/167 (23%)
		TM4SF9_like_LEL	115..235	CDD:239412	33/147 (22%)