Protein Alignment Tsp68C and TSPAN3

DIOPT Version :10

• Sequence 1: NP_729926.1
• Gene: Tsp68C / 117407
• FlyBaseID: FBgn0043550
• Length: 362
• Species: Drosophila melanogaster
• Sequence 2: NP_005715.1
• Gene: TSPAN3 / 10099
• HGNCID: 17752
• Length: 253
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 61/287 - (21%)
• Similarity: 114/287 - (39%)
• Gaps: 62/287 - (21%)

  Fly     8 KFVLNLCNFLFLICGLLLVVSGLYIF---SDNKRILLSRLLAASSDRLSSLPQPLLFYIALGVAI 69
            |.||...|.:|.....:|...|.|:|   .|.....        .|..:.:|       |:.:..
Human    10 KTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFF--------EDVYTLIP-------AVVIIA 59

  Fly    70 AGFVATLAAVVGFWASCLHTYCFLTIYFLSVVVLLLTESVLCLAITLWPHCLGI---SLDETQMV 131
            .|.:..:..::|..|:...:.|.|..:.:.::::.:||.|:.:        ||.   :..|.::.
Human    60 VGALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVV--------LGYVYRAKVENEVD 116

  Fly   132 RSLQ---SNYGVPGQEQFTNALDLAQVRFGCCGMRSSLDYDTSLWRLQGYGQRNWPVPLSCC--F 191
            ||:|   ..|.....:..:.|:|..|.:..|||:.:..|::.:.|..:   .:|..||||||  .
Human   117 RSIQKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKE---TKNQSVPLSCCRET 178

  Fly   192 LKNAGHSMAYLDPKPANESMCQSLERLSYERERHTESCLPHLDNWYREQYSIFLGASLILAMIEF 256
            ..|...|:|:  |.......|::|.      .:..:..:.|:           :.|:|..|.|:
Human   179 ASNCNGSLAH--PSDLYAEGCEALV------VKKLQEIMMHV-----------IWAALAFAAIQ- 223

  Fly   257 CVLLAIIMSCTGLASQRARLKKPVQEM 283
              ||.::.:|..|.   .|.:.|..|:
Human   224 --LLGMLCACIVLC---RRSRDPAYEL 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp68C	NP_729926.1	Tetraspanin	8..>161	CDD:459767	32/161 (20%)
		tetraspanin_LEL	117..241	CDD:239401	29/131 (22%)
TSPAN3	NP_005715.1	Tetraspanin	9..235	CDD:459767	57/272 (21%)
		TM4SF8_like_LEL	104..210	CDD:239416	27/116 (23%)