Protein Alignment betaTub65B and Tubb5

DIOPT Version :10

• Sequence 1: NP_729172.1
• Gene: betaTub65B / 117406
• FlyBaseID: FBgn0052396
• Length: 462
• Species: Drosophila melanogaster
• Sequence 2: NP_035785.1
• Gene: Tubb5 / 22154
• MGIID: 107812
• Length: 444
• Species: Mus musculus
• Alignment Length: 457
• Identity: 240/457 - (52%)
• Similarity: 320/457 - (70%)
• Gaps: 19/457 - (4%)

  Fly     1 MREIVTLQIGGAGNAIGDSFWHVISHEHGVDYASGRFGGTSPLQLERINVFFNATASKRFYARTI 65
            |||||.:|.|..||.||..||.|||.|||:| .:|.:.|.|.|||:||:|::|.....::..|.|
Mouse     1 MREIVHIQAGQCGNQIGAKFWEVISDEHGID-PTGTYHGDSDLQLDRISVYYNEATGGKYVPRAI 64

  Fly    66 LIDTEASTIQRLNAS--SQLYRPENFVAGSESAGNNFARGYHTDGAAILDQVLENTRREVESVDS 128
            |:|.|..|:..:.:.  .|::||:|||.|...||||:|:|::|:||.::|.||:..|:|.||.|.
Mouse    65 LVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDC 129

  Fly   129 LQGFQLLHSIGGGTGSGLTSLIMEALVEQYPDNLLCNYVTIPSPNMSQVVVEPYNALLSTPALVN 193
            ||||||.||:|||||||:.:|::..:.|:|||.::..:..:|||.:|..|||||||.||...||.
Mouse   130 LQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVE 194

  Fly   194 NSHLTFCLDNEALFQICNRNLKLKMSGYEHINHIVALTMSGITTCLRFPGQLNAGLRKIYVNMVP 258
            |:..|:|:|||||:.||.|.|||....|..:||:|:.||||:||||||||||||.|||:.|||||
Mouse   195 NTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVP 259

  Fly   259 FPRLHFLIPGFAPLVTCKQQQFSKGTVSELVQQIFYSNNLLCAIDLRKGKLLTAAGIFRGRMSPR 323
            ||||||.:||||||.:...||:...||.||.||:|.:.|::.|.|.|.|:.||.|.:||||||.:
Mouse   260 FPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRMSMK 324

  Fly   324 EVDQLMTGVRNKNINNFVDWIPNNIKTAICDIPPRGLKMSATFIGNTTAIQTLFQRLLDASMSML 388
            |||:.|..|:|||.:.||:|||||:|||:||||||||||:.|||||:||||.||:|:.:...:|.
Mouse   325 EVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAMF 389

  Fly   389 RRKAHLHWYTGEGMEEQEFQDAQQELQAIIDDYR----SSAEGEDSGGGGGGGGGRSGSAESGEE 449
            ||||.|||||||||:|.||.:|:..:..::.:|:    ::||.|:..|            |..||
Mouse   390 RRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEEDFG------------EEAEE 442

  Fly   450 EA 451
            ||
Mouse   443 EA 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTub65B	NP_729172.1	beta_tubulin	2..425	CDD:276956	230/428 (54%)
Tubb5	NP_035785.1	PLN00220	1..429	CDD:215107	231/428 (54%)
		MREI motif. /evidence=ECO:0000250|UniProtKB:P07437	1..4		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	423..444		7/32 (22%)