Protein Alignment betaTub65B and Tubb3

DIOPT Version :10

• Sequence 1: NP_729172.1
• Gene: betaTub65B / 117406
• FlyBaseID: FBgn0052396
• Length: 462
• Species: Drosophila melanogaster
• Sequence 2: NP_075768.1
• Gene: Tubb3 / 22152
• MGIID: 107813
• Length: 450
• Species: Mus musculus
• Alignment Length: 435
• Identity: 234/435 - (53%)
• Similarity: 311/435 - (71%)
• Gaps: 5/435 - (1%)

  Fly     1 MREIVTLQIGGAGNAIGDSFWHVISHEHGVDYASGRFGGTSPLQLERINVFFNATASKRFYARTI 65
            |||||.:|.|..||.||..||.|||.|||:| .||.:.|.|.||||||:|::|..:|.::..|.|
Mouse     1 MREIVHIQAGQCGNQIGAKFWEVISDEHGID-PSGNYVGDSDLQLERISVYYNEASSHKYVPRAI 64

  Fly    66 LIDTEASTIQ--RLNASSQLYRPENFVAGSESAGNNFARGYHTDGAAILDQVLENTRREVESVDS 128
            |:|.|..|:.  |..|...|:||:||:.|...||||:|:|::|:||.::|.||:..|:|.|:.|.
Mouse    65 LVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKECENCDC 129

  Fly   129 LQGFQLLHSIGGGTGSGLTSLIMEALVEQYPDNLLCNYVTIPSPNMSQVVVEPYNALLSTPALVN 193
            ||||||.||:|||||||:.:|::..:.|:|||.::..:..:|||.:|..|||||||.||...||.
Mouse   130 LQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSIHQLVE 194

  Fly   194 NSHLTFCLDNEALFQICNRNLKLKMSGYEHINHIVALTMSGITTCLRFPGQLNAGLRKIYVNMVP 258
            |:..|:|:|||||:.||.|.|||....|..:||:|:.||||:||.|||||||||.|||:.|||||
Mouse   195 NTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSLRFPGQLNADLRKLAVNMVP 259

  Fly   259 FPRLHFLIPGFAPLVTCKQQQFSKGTVSELVQQIFYSNNLLCAIDLRKGKLLTAAGIFRGRMSPR 323
            ||||||.:||||||.....||:...||.||.||:|.:.|::.|.|.|.|:.||.|.:||||||.:
Mouse   260 FPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVATVFRGRMSMK 324

  Fly   324 EVDQLMTGVRNKNINNFVDWIPNNIKTAICDIPPRGLKMSATFIGNTTAIQTLFQRLLDASMSML 388
            |||:.|..:::||.:.||:|||||:|.|:|||||||||||:|||||:||||.||:|:.:...:|.
Mouse   325 EVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRGLKMSSTFIGNSTAIQELFKRISEQFTAMF 389

  Fly   389 RRKAHLHWYTGEGMEEQEFQDAQQELQAIIDDYR--SSAEGEDSG 431
            ||||.|||||||||:|.||.:|:..:..::.:|:  ..|..|:.|
Mouse   390 RRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEG 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTub65B	NP_729172.1	beta_tubulin	2..425	CDD:276956	230/426 (54%)
Tubb3	NP_075768.1	PLN00220	1..447	CDD:215107	234/435 (54%)
		MREI motif. /evidence=ECO:0000250|UniProtKB:P07437	1..4		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	422..450		4/13 (31%)