Protein Alignment betaTub65B and Tubb2a

DIOPT Version :10

• Sequence 1: NP_729172.1
• Gene: betaTub65B / 117406
• FlyBaseID: FBgn0052396
• Length: 462
• Species: Drosophila melanogaster
• Sequence 2: NP_033476.1
• Gene: Tubb2a / 22151
• MGIID: 107861
• Length: 445
• Species: Mus musculus
• Alignment Length: 455
• Identity: 244/455 - (53%)
• Similarity: 319/455 - (70%)
• Gaps: 14/455 - (3%)

  Fly     1 MREIVTLQIGGAGNAIGDSFWHVISHEHGVDYASGRFGGTSPLQLERINVFFNATASKRFYARTI 65
            |||||.:|.|..||.||..||.|||.|||:| .:|.:.|.|.||||||||::|..|..::..|.|
Mouse     1 MREIVHIQAGQCGNQIGAKFWEVISDEHGID-PTGSYHGDSDLQLERINVYYNEAAGNKYVPRAI 64

  Fly    66 LIDTEASTIQRLNAS--SQLYRPENFVAGSESAGNNFARGYHTDGAAILDQVLENTRREVESVDS 128
            |:|.|..|:..:.:.  .|::||:|||.|...||||:|:|::|:||.::|.||:..|:|.||.|.
Mouse    65 LVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDC 129

  Fly   129 LQGFQLLHSIGGGTGSGLTSLIMEALVEQYPDNLLCNYVTIPSPNMSQVVVEPYNALLSTPALVN 193
            ||||||.||:|||||||:.:|::..:.|:|||.::..:..:|||.:|..|||||||.||...||.
Mouse   130 LQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVE 194

  Fly   194 NSHLTFCLDNEALFQICNRNLKLKMSGYEHINHIVALTMSGITTCLRFPGQLNAGLRKIYVNMVP 258
            |:..|:.:|||||:.||.|.|||....|..:||:|:.||||:||||||||||||.|||:.|||||
Mouse   195 NTDETYSIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVP 259

  Fly   259 FPRLHFLIPGFAPLVTCKQQQFSKGTVSELVQQIFYSNNLLCAIDLRKGKLLTAAGIFRGRMSPR 323
            ||||||.:||||||.:...||:...||.||.||:|.|.|::.|.|.|.|:.||.|.|||||||.:
Mouse   260 FPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMK 324

  Fly   324 EVDQLMTGVRNKNINNFVDWIPNNIKTAICDIPPRGLKMSATFIGNTTAIQTLFQRLLDASMSML 388
            |||:.|..|:|||.:.||:|||||:|||:|||||||||||||||||:||||.||:|:.:...:|.
Mouse   325 EVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMF 389

  Fly   389 RRKAHLHWYTGEGMEEQEFQDAQQELQAIIDDYR--SSAEGEDSGGGGGGGGGRSGSAESGEEEA 451
            ||||.|||||||||:|.||.:|:..:..::.:|:  ..|..::.|         ....|.||:||
Mouse   390 RRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEQG---------EFEEEEGEDEA 445

  Fly   452  451
            Mouse   446  445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTub65B	NP_729172.1	beta_tubulin	2..425	CDD:276956	236/426 (55%)
Tubb2a	NP_033476.1	PLN00220	1..430	CDD:215107	238/429 (55%)
		MREI motif. /evidence=ECO:0000250|UniProtKB:P07437	1..4		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	422..445		6/31 (19%)