Protein Alignment betaTub65B and tba-4

DIOPT Version :10

• Sequence 1: NP_729172.1
• Gene: betaTub65B / 117406
• FlyBaseID: FBgn0052396
• Length: 462
• Species: Drosophila melanogaster
• Sequence 2: NP_496351.1
• Gene: tba-4 / 174680
• WormBaseID: WBGene00006530
• Length: 448
• Species: Caenorhabditis elegans
• Alignment Length: 463
• Identity: 159/463 - (34%)
• Similarity: 247/463 - (53%)
• Gaps: 30/463 - (6%)

  Fly     1 MREIVTLQIGGAGNAIGDSFWHVISHEHGVDYASGRFGGTSPLQLER----INVFFNATASKRFY 61
            |||::::.:|.||..||::.|.:...|||:     :..||.|.:.:.    ...||:.|.:.|:.
 Worm     1 MREVISIHVGQAGVQIGNACWELYCLEHGI-----QPDGTMPSEQQNEGGSFTTFFSDTGNGRYV 60

  Fly    62 ARTILIDTEASTIQRLNASS--QLYRPENFVAGSESAGNNFARGYHTDGAAILDQVLENTRREVE 124
            .|:|.:|.|.:.:..:...:  :|:.||..:.|.|.|.||:|||::|.|..::|..|:..||..:
 Worm    61 PRSIFVDLEPTVVDEIRTGNYKKLFHPEQMITGKEDAANNYARGHYTVGKELIDTTLDRIRRLAD 125

  Fly   125 SVDSLQGFQLLHSIGGGTGSGLTSLIMEALVEQYPDNLLCNYVTIPSPNMSQVVVEPYNALLSTP 189
            :...||||.:.||.|||||||.|||:||.|...|.......:...|:|.:|..||||||::|:|.
 Worm   126 NCSGLQGFFVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTH 190

  Fly   190 ALVNNSHLTFCLDNEALFQICNRNLKLKMSGYEHINHIVALTMSGITTCLRFPGQLNAGLRKIYV 254
            ..:.:|...|.:||||::.||.|||.:....|.::|.|::..:|.||..|||.|.||..|.:...
 Worm   191 TTLEHSDCAFMVDNEAIYDICKRNLDVDRPSYTNLNRIISQVVSSITASLRFDGALNVDLNEFQT 255

  Fly   255 NMVPFPRLHFLIPGFAPLVTCKQQQFSKGTVSELVQQIFYSNNLLCAIDLRKGKLLTAAGIFRGR 319
            |:||:||:||.:..:.||::.::......:|:::....|...|.:...|.|.||.:....::||.
 Worm   256 NLVPYPRIHFPLASYTPLISAEKAYHEALSVNDITNSCFEPANQMVKCDPRNGKYMAVCLLYRGD 320

  Fly   320 MSPREVDQLMTGVRNKNINNFVDWIPNNIKTAICDIPP--------RGLKMSATFIGNTTAIQTL 376
            :.|::|:..:|.::.|....||||.|...|..|...||        ..:..:...:.|||||...
 Worm   321 VVPKDVNTAITAIKTKRSVQFVDWCPTGFKVGINYQPPTVVPGGDLAKVPRAVCMLSNTTAIAEA 385

  Fly   377 FQRLLDASMSMLRRKAHLHWYTGEGMEEQEFQDAQQELQAIIDDYRSSAEGEDSGGGGGGGGGRS 441
            :.||......|..::|.:|||.||||||.||.:|:::|.|:..||..  .|.||         ..
 Worm   386 WSRLDYKFDLMYAKRAFVHWYVGEGMEEGEFTEAREDLAALEKDYEE--VGADS---------NE 439

  Fly   442 GSAESGEE 449
            |..|.|||
 Worm   440 GLEEDGEE 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
betaTub65B	NP_729172.1	beta_tubulin	2..425	CDD:276956	150/436 (34%)
tba-4	NP_496351.1	PTZ00335	1..446	CDD:185562	156/460 (34%)