DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Desat1 and scdb

DIOPT Version :9

Sequence 1:	NP_652731.1	Gene:	Desat1 / 117369	FlyBaseID:	FBgn0086687	Length:	383	Species:	Drosophila melanogaster
Sequence 2:	XP_005156902.1	Gene:	scdb / 553734	ZFINID:	ZDB-GENE-050522-12	Length:	380	Species:	Danio rerio

Alignment Length:	331	Identity:	171/331 - (51%)
Similarity:	222/331 - (67%)	Gaps:	8/331 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 SPTKLQEDSTGVLFECDVETTDGGLVKDITVMKKAEKRRLKLVWRNIIAFGYLHLAALYGAYLM- 92
            |..:.|..||..:  .||.||...:..|..|.|......:::||||:|....|||.||||..::
Zfish    53 SQARRQYTSTEAM--ADVTTTTEDVFDDSYVEKPGPSPPVQIVWRNVILMTLLHLGALYGMTILP 115

  Fly    93 -VTSAKWQTCILAYFLYVISGLGITAGAHRLWAHRSYKAKWPLRVILVIFNTIAFQDAAYHWARD 156
             |:|.   |.|.....:::|.|||||||||||:||||:|..|||:.|.:.|::|||:..|.||||
Zfish   116 FVSSL---TLIWTGVCFMVSALGITAGAHRLWSHRSYRASLPLRIFLAVANSMAFQNDIYEWARD 177

  Fly   157 HRVHHKYSETDADPHNATRGFFFSHVGWLLCKKHPEVKAKGKGVDLSDLRADPILMFQKKYYMIL 221
            ||||||:||||||||||.|||||:|:||||.:|||||..||:.:...||:||.::|||:::|.:.
Zfish   178 HRVHHKFSETDADPHNARRGFFFAHIGWLLVRKHPEVIDKGRKLTFEDLKADSVVMFQRRHYKLS 242

  Fly   222 MPIACFIIPTVVPMYAWGESFMNAWFVATMFRWCFILNVTWLVNSAAHKFGGRPYDKFINPSENI 286
            :.:.||:|||:||.:.|.||...|:.|..:.|:..:||.|||||||||.:|.||||..|||.||.
Zfish   243 VVVMCFLIPTLVPWFFWEESLWTAYLVPCLLRYAVVLNATWLVNSAAHMWGMRPYDHNINPRENK 307

  Fly   287 SVAILAFGEGWHNYHHVFPWDYKTAEFGKYSLNFTTAFIDFFAKIGWAYDLKTVSTDIIKKRVKR 351
            .||..|.|||:|||||.||.||.|:|||. .||.|.||||....:|.|.|.:.|:.:.|..||:|
Zfish   308 FVAFSAIGEGFHNYHHTFPHDYATSEFGS-RLNVTKAFIDLMCFLGLANDCRRVTHETILARVQR 371

  Fly   352 TGDGTH 357
            ||||:|
Zfish   372 TGDGSH 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Desat1	NP_652731.1	Delta9-FADS-like	97..338	CDD:239582	136/240 (57%)
Desat1	NP_652731.1	FA_desaturase	98..305	CDD:278890	118/206 (57%)
scdb	XP_005156902.1	Delta9-FADS-like	118..358	CDD:239582	137/243 (56%)
scdb	XP_005156902.1	FA_desaturase	122..326	CDD:278890	117/203 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	280	1.000	Domainoid score	I1638
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	359	1.000	Inparanoid score	I2172
OMA	1	1.010	-	-		QHG63267
OrthoDB	1	1.010	-	-		D296120at33208
OrthoFinder	1	1.000	-	-		FOG0000495
OrthoInspector	1	1.000	-	-		mtm6351
orthoMCL	1	0.900	-	-		OOG6_100468
Panther	1	1.100	-	-	LDO	PTHR11351
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16
SonicParanoid	1	1.000	-	-		X207
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	13.010