DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Desat1 and fat-7

DIOPT Version :9

Sequence 1:	NP_652731.1	Gene:	Desat1 / 117369	FlyBaseID:	FBgn0086687	Length:	383	Species:	Drosophila melanogaster
Sequence 2:	NP_504814.1	Gene:	fat-7 / 179100	WormBaseID:	WBGene00001399	Length:	338	Species:	Caenorhabditis elegans

Alignment Length:	301	Identity:	152/301 - (50%)
Similarity:	215/301 - (71%)	Gaps:	7/301 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 ITVMKKAEK--RRLKLVWRNIIAFGYLHLAALYGAYLMVTSAKWQTCILAYFLYVISGLGITAGA 119
            :.|.::::|  .::::||||:..|..||:||..|.|.:|..|||||.:.::.|||.||.||||||
Worm    31 LQVQEESKKIPYKMEIVWRNVALFAALHVAAAIGLYELVFHAKWQTAVFSFALYVFSGFGITAGA 95

  Fly   120 HRLWAHRSYKAKWPLRVILVIFNTIAFQDAAYHWARDHRVHHKYSETDADPHNATRGFFFSHVGW 184
            ||||:|:||||..|:|:.|::.|.||.|:....||||||.|||:::|||||||.||||||:|:||
Worm    96 HRLWSHKSYKATTPMRIFLMLLNNIALQNDIIEWARDHRCHHKWTDTDADPHNTTRGFFFTHMGW 160

  Fly   185 LLCKKHPEVKAKGKGVDLSDLRADPILMFQKKYYMILMPIACFIIPTVVPMYAWGESFMNAWFVA 249
            ||.:|||:||..|..:|||||.:||:|:||:|:|..|:.:.|||:||::|:|.|.|:...|::||
Worm   161 LLVRKHPQVKEHGGKLDLSDLFSDPVLVFQRKHYFPLVILFCFILPTIIPVYFWKETAFIAFYVA 225

  Fly   250 TMFRWCFILNVTWLVNSAAHKFGGRPYDKFINPSENISVAILAFGEGWHNYHHVFPWDYKTAEFG 314
            ..||:||.|:.||.:|||||.||.:|||..::..||:...::|.|||.||:||.||.||:.:|
Worm   226 GTFRYCFTLHATWCINSAAHYFGWKPYDTSVSAVENVFTTVVAVGEGGHNFHHTFPQDYRASE-- 288

  Fly   315 KYSL--NFTTAFIDFFAKIGWAYDLKTVSTDIIKKRVKRTG 353
             |||  |:|...||..|.:|..||.||::.:.|.::|...|
Worm   289 -YSLIYNWTRVLIDTAAVLGLVYDRKTIADEFISRQVANHG 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Desat1	NP_652731.1	Delta9-FADS-like	97..338	CDD:239582	132/242 (55%)
Desat1	NP_652731.1	FA_desaturase	98..305	CDD:278890	115/206 (56%)
fat-7	NP_504814.1	Delta9-FADS-like	73..313	CDD:239582	132/242 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163577
Domainoid	1	1.000	284	1.000	Domainoid score	I857
eggNOG	1	0.900	-	-		E1_COG1398
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	342	1.000	Inparanoid score	I1385
Isobase	1	0.950	-	0.837287	Normalized mean entropy	S1208
OMA	1	1.010	-	-		QHG63267
OrthoDB	1	1.010	-	-		D296120at33208
OrthoFinder	1	1.000	-	-		FOG0000495
OrthoInspector	1	1.000	-	-		mtm4822
orthoMCL	1	0.900	-	-		OOG6_100468
Panther	1	1.100	-	-	O	PTHR11351
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X207
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.720