DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Desat1 and fat-6

DIOPT Version :9

Sequence 1:	NP_652731.1	Gene:	Desat1 / 117369	FlyBaseID:	FBgn0086687	Length:	383	Species:	Drosophila melanogaster
Sequence 2:	NP_001255595.1	Gene:	fat-6 / 178122	WormBaseID:	WBGene00001398	Length:	339	Species:	Caenorhabditis elegans

Alignment Length:	316	Identity:	159/316 - (50%)
Similarity:	216/316 - (68%)	Gaps:	14/316 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 DGG-----LVKD----ITVMKKAEK--RRLKLVWRNIIAFGYLHLAALYGAYLMVTSAKWQTCIL 103
            |||     |..|    |.:.::::|  .::::||||:..|..||.||..|.|.::..|||||.|.
Worm    16 DGGPETQYLAVDPNEIIQLQEESKKIPYKMEIVWRNVALFAALHFAAAIGLYQLIFEAKWQTVIF 80

  Fly   104 AYFLYVISGLGITAGAHRLWAHRSYKAKWPLRVILVIFNTIAFQDAAYHWARDHRVHHKYSETDA 168
            .:.|||..|.||||||||||:|:||||..|:|:.|:|.|.||.|:....||||||.|||:::|||
Worm    81 TFLLYVFGGFGITAGAHRLWSHKSYKATTPMRIFLMILNNIALQNDVIEWARDHRCHHKWTDTDA 145

  Fly   169 DPHNATRGFFFSHVGWLLCKKHPEVKAKGKGVDLSDLRADPILMFQKKYYMILMPIACFIIPTVV 233
            ||||.||||||:|:||||.:|||:||.:|..:|:|||.:||:|:||:|:|..|:.:.|||:||::
Worm   146 DPHNTTRGFFFAHMGWLLVRKHPQVKEQGAKLDMSDLLSDPVLVFQRKHYFPLVILCCFILPTII 210

  Fly   234 PMYAWGESFMNAWFVATMFRWCFILNVTWLVNSAAHKFGGRPYDKFINPSENISVAILAFGEGWH 298
            |:|.|.|:...|::.|..||:||.|:.||.:|||||.||.:|||..|.|.||:...|.|.|||.|
Worm   211 PVYFWKETAFIAFYTAGTFRYCFTLHATWCINSAAHYFGWKPYDSSITPVENVFTTIAAVGEGGH 275

  Fly   299 NYHHVFPWDYKTAEFG-KYSLNFTTAFIDFFAKIGWAYDLKTVSTDIIKKRVKRTG 353
            |:||.||.||:|:|:. ||  |:|...||..|.:|..||.||...:||.::|...|
Worm   276 NFHHTFPQDYRTSEYSLKY--NWTRVLIDTAAALGLVYDRKTACDEIIGRQVSNHG 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Desat1	NP_652731.1	Delta9-FADS-like	97..338	CDD:239582	134/241 (56%)
Desat1	NP_652731.1	FA_desaturase	98..305	CDD:278890	117/206 (57%)
fat-6	NP_001255595.1	Delta9-FADS-like	74..314	CDD:239582	134/241 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163573
Domainoid	1	1.000	284	1.000	Domainoid score	I857
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	342	1.000	Inparanoid score	I1385
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG63267
OrthoDB	1	1.010	-	-		D296120at33208
OrthoFinder	1	1.000	-	-		FOG0000495
OrthoInspector	1	1.000	-	-		mtm4822
orthoMCL	1	0.900	-	-		OOG6_100468
Panther	1	1.100	-	-	LDO	PTHR11351
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16
SonicParanoid	1	1.000	-	-		X207
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.940