Protein Alignment prt and slc18a3

DIOPT Version :9

• Sequence 1: NP_001097887.1
• Gene: prt / 117368
• FlyBaseID: FBgn0043005
• Length: 602
• Species: Drosophila melanogaster
• Sequence 2: NP_001072859.1
• Gene: slc18a3 / 780320
• XenbaseID: XB-GENE-965085
• Length: 524
• Species: Xenopus tropicalis
• Alignment Length: 575
• Identity: 156/575 - (27%)
• Similarity: 255/575 - (44%)
• Gaps: 149/575 - (25%)

  Fly    45 RCLIAVIVYLALLLDNMLLTVIVPILPDYLASLEADTSSAVVLSLEDTSSFSKLGYRSGESPGGG 109
            |.:|.:||.:||.|||||..|||||:|||:.:|.||...|
 Frog    39 RRIILIIVCVALFLDNMLYMVIVPIIPDYIQNLRADREHA------------------------- 78

  Fly   110 HPQLYISKHPIPGKSMVNFTLLQLSTEATTTTTSIATTTNSPHNSTSMQSPPKLTVGQSGGTNVT 174
                         ||:
 Frog    79 -------------KSI------------------------------------------------- 81

  Fly   175 GIGHKSRNRKLASGHPPTHDNSSNDNSNKELTL------TQENGSIGLLLAMKALVQLIFNPIVG 233
                                |||:...||...:      ..|:..||:|.|.||::||:.||:.|
 Frog    82 --------------------NSSSQYRNKSFAIRPQYPAENEDMQIGVLFASKAILQLLINPLSG 126

  Fly   234 NASSKFGYRLPIVVGTFFLLLSSLVFTVGESYWALLVARAVQGVGSACINICGMSLVAQHYPEEA 298
            ....:.||.:|:::|...|..|:::|...|:|..|.|||::||:|||..:..|::::|..|.|||
 Frog   127 TFIDRVGYDIPLLIGLVVLFFSTVIFAFAENYATLFVARSLQGLGSAFADTSGIAMIADTYTEEA 191

  Fly   299 RRSKVMGIILGSIALGVLLGYPFGGILYDLMGKSAPFIILSTLMFLSLGLQLLTMDLTVQPEVVV 363
            .|||.:||.|..|:.|.|:..|||||||..:||..||::|:::..:. |:.||   |.::|   .
 Frog   192 ERSKALGIALAFISFGSLVAPPFGGILYQFVGKRMPFLVLASIALID-GVLLL---LVIKP---F 249

  Fly   364 EDR---------PKWRSLLECKMILAIVLAIWFSTSTMAMLEPCLPIWLIQYLKPNKWQLGTVFI 419
            .:|         |..|.::: ..|..:..|:......:|.|||.:..|:...:..::||:|..::
 Frog   250 TNRTRANMPIGTPIHRLMID-PYIAVVAGALTTCNIPLAFLEPTIANWMKTTMDASEWQMGLTWL 313

  Fly   420 PDSVGYFVGTNFFGSIA--YKYGQVKVSCISLLLVGVASILIPSATTVAQLLLPHFALGLGIGVI 482
            |....:.:|......:|  |.:.|.....|.::::|.:|..:|:.....:|::|...:..||.::
 Frog   314 PAFFPHVLGVYITVKLAANYPHYQWFYGAIGMVIIGASSCTVPACKNFWELIVPLCGICFGIALV 378

  Fly   483 DAALVPLLATFVDATLAQEDQGEGSSSMSSYGTVYAIQQTSVSLAYCLAPLIGGELAQTFGFAWL 547
            |.||:|.||..||.           ..:|.||:||||...|..:||.|.|::..::..|.||..|
 Frog   379 DTALLPTLALLVDV-----------RHVSVYGSVYAIADISYCVAYALGPVVASQIVHTTGFTQL 432

  Fly   548 MRIVGIFNMIYGPILVYLHQKYDPKALREQHNDMLLQSSGRGSRYKQLYNSMDVE 602
            ...:|:.|::|.|.|::|......|....:.| :||:...:|     ||:::.:|
 Frog   433 NLGMGLANVLYAPALLFLRNVCQMKPSHSERN-ILLEEGPKG-----LYDTIKME 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prt	NP_001097887.1	MFS	212..565	CDD:119392	116/363 (32%)
		MFS_1	212..532	CDD:284993	106/330 (32%)
slc18a3	NP_001072859.1	MFS_SLC18A3_VAChT	43..451	CDD:340941	145/533 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59108
OrthoDB	1	1.010	-	-		D406900at33208
OrthoFinder	1	1.000	-	-		FOG0000700
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.930