Protein Alignment prt and slc18a2

DIOPT Version :10

• Sequence 1: NP_001097887.1
• Gene: prt / 117368
• FlyBaseID: FBgn0043005
• Length: 602
• Species: Drosophila melanogaster
• Sequence 2: NP_001243154.1
• Gene: slc18a2 / 553304
• ZFINID: ZDB-GENE-080514-1
• Length: 515
• Species: Danio rerio
• Alignment Length: 575
• Identity: 191/575 - (33%)
• Similarity: 304/575 - (52%)
• Gaps: 100/575 - (17%)

  Fly    44 NRCLIAVIVYLALLLDNMLLTVIVPILPDYLASLEADTSSAV----VLSLEDTSSFSKLGYRSGE 104
            :|.||.:||::|||||||||||:|||:|.||.:::.:.:..|    :..|..:|:|..:
Zfish    22 SRRLILLIVFIALLLDNMLLTVVVPIIPSYLYTVDDEAAQMVKNHSMTPLSPSSTFQSI------ 80

  Fly   105 SPGGGHPQLYISKHPIPGKSMVNFTLLQLSTEATTTTTSIATTTNSPHNSTSMQSPPKLTVGQSG 169
                  ..||.:...:.|.|.      |:||..   ..|:|.|..||.|.:..
Zfish    81 ------VSLYDNTTRVTGFSP------QMSTAG---PMSLAPTFVSPQNQSDC------------ 118

  Fly   170 GTNVTGIGHKSRNRKLASGHPPTHDNSSNDNSNKELTLTQENGSIGLLLAMKALVQLIFNPIVGN 234
                                 |..|:.          |..||..:|||.|.||.||||.||.:|.
Zfish   119 ---------------------PKADDQ----------LLNENVKVGLLFASKATVQLITNPFIGP 152

  Fly   235 ASSKFGYRLPIVVGTFFLLLSSLVFTVGESYWALLVARAVQGVGSACINICGMSLVAQHYPEEAR 299
            .:::.||::|:..|...:.:|:::|....||..|.:||::|||||:|.::.||.::|..|.::..
Zfish   153 LTNRIGYQIPMFAGFCIMFVSTIMFAFSSSYTLLFLARSLQGVGSSCSSVAGMGMLASVYTDDEE 217

  Fly   300 RSKVMGIILGSIALGVLLGYPFGGILYDLMGKSAPFIILSTLMFLSLGLQLLTMDLTVQPEVVVE 364
            |...:||.||.:|:|||:|.|||.::|:.:||:|||:||:.|..|...|||..:    ||..|..
Zfish   218 RGNAIGIALGGLAMGVLVGPPFGSVMYEFVGKTAPFLILAVLAVLDGALQLFVL----QPSKVEP 278

  Fly   365 DRPKWRS---LLECKMILAIVLAIWFSTSTMAMLEPCLPIWLIQYLKPNKWQLGTVFIPDSVGYF 426
            :..|..|   |::...||....:|.|:...:|||||.||||:::.:.|.|||||..|:|.|:.|.
Zfish   279 ESQKGTSLITLMKDPYILIAAGSICFANMAIAMLEPALPIWMMETMCPRKWQLGIAFVPASISYL 343

  Fly   427 VGTNFFGSIAYKYGQVKVSCISLLLVGVASILIPSATTVAQLLLPHFALGLGIGVIDAALVPLLA 491
            :|||.|..:|:|.|:...|.|.:||||::.:.:|.|..:..|::|:|.:|..||::|::::|::.
Zfish   344 IGTNIFAVLAHKMGRWLCSLIGMLLVGISILCVPLAKDIYGLIVPNFGVGFAIGMVDSSMMPIMG 408

  Fly   492 TFVDATLAQEDQGEGSSSMSSYGTVYAIQQTSVSLAYCLAPLIGGELAQTFGFAWLMRIVGIFNM 556
            ..||.           ..:|.||:||||...:..:.:.|.|..||.:|::.||.|||.|:|:.::
Zfish   409 YLVDL-----------RHVSVYGSVYAIADVAFCMGFALGPSAGGAIARSIGFPWLMTIIGLVDI 462

  Fly   557 IYGPILVYLHQKYDPKALREQHNDMLLQS---------SGRGSRYKQLYNSMDVE 602
            ::.|:..:|.   :|.| .|:...:|:.|         |.:||.| |:.:..|.|
Zfish   463 MFAPLCFFLR---NPPA-NEEKMAILMDSNCSMKTRSYSTQGSSY-QMGDDFDPE 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prt	NP_001097887.1	MFS_SLC18A1_2_VAT1_2	209..566	CDD:340942	136/359 (38%)
slc18a2	NP_001243154.1	MFS_SLC18A1_2_VAT1_2	26..472	CDD:340942	176/524 (34%)