Protein Alignment prt and unc-17

DIOPT Version :10

• Sequence 1: NP_001097887.1
• Gene: prt / 117368
• FlyBaseID: FBgn0043005
• Length: 602
• Species: Drosophila melanogaster
• Sequence 2: NP_001379838.1
• Gene: unc-17 / 24105312
• WormBaseID: WBGene00006756
• Length: 532
• Species: Caenorhabditis elegans
• Alignment Length: 570
• Identity: 154/570 - (27%)
• Similarity: 241/570 - (42%)
• Gaps: 138/570 - (24%)

  Fly    42 SSNRCLIAVIVYLALLLDNMLLTVIVPILPDYLASLEADTSSAVVLSLEDTSSFSKLGYRSGESP 106
            :..:|:: |||.:||||||||..|||||:|.||..:.
 Worm    28 NQKKCVL-VIVSIALLLDNMLYMVIVPIIPKYLRDIH---------------------------- 63

  Fly   107 GGGHPQLYISKHPIPGKSMVNFTLLQLSTEATTTTTSIATTTNSPHNSTSMQSPPKLTVGQSGGT 171
                                |:.:                |....||.||..:.....|.:.||
 Worm    64 --------------------NYQV----------------TFEGYHNETSQLANGTYLVREVGG- 91

  Fly   172 NVTGIGHKSRNRKLASGHPPTHDNSSNDNSNKELTLTQENGSIGLLLAMKALVQLIFNPIVGNAS 236
                                            .:....|...:|.|.|.|||:|:..||..|...
 Worm    92 --------------------------------RINFLDEELELGWLFASKALLQIFVNPFSGYII 124

  Fly   237 SKFGYRLPIVVGTFFLLLSSLVFTVGESYWALLVARAVQGVGSACINICGMSLVAQHYPEEARRS 301
            .:.||.:|:::|...:..|:.:|.:|:||..||.||::||.|||..:..|::::|..:.||..||
 Worm   125 DRVGYEIPMILGLCTMFFSTAIFALGKSYGVLLFARSLQGFGSAFADTSGLAMIADRFTEENERS 189

  Fly   302 KVMGIILGSIALGVLLGYPFGGILYDLMGKSAPFIILSTLMFLSLGLQLLTMDLTVQPE------ 360
            ..:||.|..|:.|.|:..|||.:||.|.||..||:|||   |:.|. ..:.:.:.:.|.
 Worm   190 AALGIALAFISFGCLVAPPFGSVLYSLAGKPVPFLILS---FVCLA-DAIAVFMVINPHRRGTDS 250

  Fly   361 --VVVEDRPKWRSLLECKMILAIVLAIWFSTSTMAMLEPCLPIWLIQYLKPNK-WQLGTV----F 418
              ..|:..|.||..:: ..|.....|:..:..::|.|||.:..|:.:.:.... |.:|.:    |
 Worm   251 HGEKVQGTPMWRLFMD-PFIACCSGALIMANVSLAFLEPTITTWMSEMMPDTPGWLVGVIWLPPF 314

  Fly   419 IPDSVGYFVGTNFFGSIAYKYGQVKVSCISLLLVGVASILIPSATTVAQLLLPHFALGLGIGVID 483
            .|..:|.:|......  |:.:....::.:.|.:.|:|...||..|:|.||::|...:..||.:||
 Worm   315 FPHVLGVYVTVKMLR--AFPHHTWAIAMVGLAMEGIACFAIPYTTSVMQLVIPLSFVCFGIALID 377

  Fly   484 AALVPLLATFVDATLAQEDQGEGSSSMSSYGTVYAIQQTSVSLAYCLAPLIGGELAQTFGFAWLM 548
            .:|:|:|...||           :..:|.||:||||...|.||||...|:|.|.:...:||..|.
 Worm   378 TSLLPMLGHLVD-----------TRHVSVYGSVYAIADISYSLAYAFGPIIAGWIVTNWGFTALN 431

  Fly   549 RIVGIFNMIYGPILVYLHQKYDPKALREQHNDMLLQSSGRGSRYKQLYNS 598
            .|:...|:.|.|:|.         .||:.|:...|.:.|..:...||.:|
 Worm   432 IIIFATNVTYAPVLF---------LLRKVHSYDTLGAKGDTAEMTQLNSS 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prt	NP_001097887.1	MFS_SLC18A1_2_VAT1_2	209..566	CDD:340942	117/369 (32%)
unc-17	NP_001379838.1	MFS_SLC18A3_VAChT	34..449	CDD:340941	145/539 (27%)