Protein Alignment prt and cat-1

DIOPT Version :9

• Sequence 1: NP_001097887.1
• Gene: prt / 117368
• FlyBaseID: FBgn0043005
• Length: 602
• Species: Drosophila melanogaster
• Sequence 2: NP_001024936.1
• Gene: cat-1 / 180837
• WormBaseID: WBGene00000295
• Length: 553
• Species: Caenorhabditis elegans
• Alignment Length: 583
• Identity: 189/583 - (32%)
• Similarity: 293/583 - (50%)
• Gaps: 113/583 - (19%)

  Fly    43 SNRCLIAVIVYLALLLDNMLLTVIVPILPDYLASLEADTSSAVVLS----------LEDTSSFS- 96
            :||.::.:|||:||.|||||||.:|||:|:||..:|....:.::.|          .||..|:.
 Worm    13 NNRKILLLIVYIALFLDNMLLTTVVPIIPEYLLRMEHPNETDILFSHNSQKRVKRQWEDDDSWDV 77

  Fly    97 --KLGYRS----GESPGGGHPQLYISKHPIPGKSMVNFTLLQLSTEATTTTTSIATTTNSPHNST 155
              |||..:    .|:|.|          |: |:|                             ..
 Worm    78 PLKLGNNADIDWDENPIG----------PV-GRS-----------------------------ER 102

  Fly   156 SMQSPPKLTVGQSGGTNVTGIGHKSRNRKL---------ASGHPP--THDNSSNDNSNKE--LTL 207
            ..:|..|              .|.|:||:.         |:..||  |.:.:....|.:|  ..|
 Worm   103 RKESDRK--------------NHNSKNREYNDRRKYMSPAAKKPPVETEEPAVRTISEEERHKLL 153

  Fly   208 TQENGSIGLLLAMKALVQLIFNPIVGNASSKFGYRLPIVVGTFFLLLSSLVFTVGESYWALLVAR 272
            ..||..:||:...||||||:.||.:|..:::.||.:|:..|...:..|:::|..|:||:.|.:||
 Worm   154 ASENVHVGLMFGSKALVQLLVNPWIGPLTNRIGYTMPMFGGFVIMFCSTILFAFGDSYFTLWLAR 218

  Fly   273 AVQGVGSACINICGMSLVAQHYPEEARRSKVMGIILGSIALGVLLGYPFGGILYDLMGKSAPFII 337
            |:|||||||.:..||.::||.||::..|...|||.||.:|||||:|.|:||:||...||..||::
 Worm   219 ALQGVGSACTSTSGMGMLAQAYPDDLERGSAMGIALGGLALGVLVGPPYGGLLYQWSGKELPFVL 283

  Fly   338 LSTLMFLSLGLQLLTMDLTVQPEVVVEDR--PKWRS---LLECKMILAIVLAIWFSTSTMAMLEP 397
            |:.|......:|.:.:    ||::   ||  |:..|   |.:...|:....||......:|||||
 Worm   284 LALLALFDGSIQFMVL----QPKI---DRGEPEGSSIKQLAKDPYIIVAAGAITIGNLGIAMLEP 341

  Fly   398 CLPIWLIQYLKPNKWQLGTVFIPDSVGYFVGTNFFGSIAYKYGQVKVSCISLLLVGVASILIPSA 462
            .||:|:::....|..:.|..|:|.|:.|.:|||.||.:|::.|:...|.|.|:::|.:.:.||||
 Worm   342 SLPLWMMESWGANSLERGAAFLPASISYLIGTNIFGPLAHRIGRWLSSFIGLVVIGFSLLSIPSA 406

  Fly   463 TTVAQLLLPHFALGLGIGVIDAALVPLLATFVDATLAQEDQGEGSSSMSSYGTVYAIQQTSVSLA 527
            |:||.|::||..||..||:|||::.||:...||.           ..:..||::|||...:...|
 Worm   407 TSVAGLIIPHALLGFSIGMIDASMFPLMGYLVDI-----------RHVGVYGSIYAIADAAFCFA 460

  Fly   528 YCLAPLIGGELAQTFGFAWLMRIVGIFNMIYGPILVYLHQKYDPKALRE---QHNDMLLQSSG 587
            :.|.|...|.|.::.||..:|.|:.:.:.:|.|::..|.   :|..|.|   |...:.|:.:|
 Worm   461 FALGPFFSGPLVKSLGFPTMMYIIAVISFLYAPLMFLLK---NPPVLIEPTPQTQSVELRQNG 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prt	NP_001097887.1	MFS	212..565	CDD:119392	133/357 (37%)
		MFS_1	212..532	CDD:284993	124/324 (38%)
cat-1	NP_001024936.1	MFS_SLC18A1_2_VAT1_2	18..499	CDD:340942	180/552 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.917438	Normalized mean entropy	S3897
OMA	1	1.010	-	-		QHG59108
OrthoDB	1	1.010	-	-		D406900at33208
OrthoFinder	1	1.000	-	-		FOG0000700
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23506
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.980