DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment prt and LOC101731380

DIOPT Version :9

Sequence 1:	NP_001097887.1	Gene:	prt / 117368	FlyBaseID:	FBgn0043005	Length:	602	Species:	Drosophila melanogaster
Sequence 2:	XP_031755164.1	Gene:	LOC101731380 / 101731380	-ID:	-	Length:	414	Species:	Xenopus tropicalis

Alignment Length:	456	Identity:	148/456 - (32%)
Similarity:	230/456 - (50%)	Gaps:	68/456 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 SKHPIPGKSMVNFTLLQLSTEATTTTTSIATTTNSPHNSTSMQSPPKLTVGQSGGTNVTGIGHKS 180
            |..|.||.|..:|.|                      |:.|..||.:|.     .||.|.:.:|.
Frog     5 STPPAPGSSFSSFLL----------------------NNESSGSPNELE-----DTNRTYVPNKE 42

  Fly   181 RNRKLASGHPPTHDNSSNDNSNKELTLTQENGSIGLLLAMKALVQLIFNPIVGNASSKFGYRLPI 245
            ...|                 |....|.:||.::|||||.||:||::|||||...:.:.||.||:
Frog    43 TICK-----------------NNTSVLQEENITVGLLLASKAIVQILFNPIVSLITYRLGYELPM 90

  Fly   246 VVGTFFLLLSSLVFTVGESYWALLVARAVQGVGSACINICGMSLVAQHYPEEARRSKVMGIILGS 310
            :.|....|.|.|:|....||..|.|||::||:|::..::.||:::|..|.::..|.:.|||.||.
Frog    91 IFGFIITLPSILLFAFASSYSLLFVARSLQGIGTSFTSVSGMAILANKYTDDKERGEAMGIALGG 155

  Fly   311 IALGVLLGYPFGGILYDLMGKSAPFIILSTLMFLSLGLQLL------TMDLTVQPEVVVEDRPKW 369
            :|||::.|.|||..:|..:||::||:||:.|..|...|:||      |..||:.       .|.:
Frog   156 VALGLVAGPPFGSAMYAFVGKASPFLILAALTLLDGALRLLILTPSKTAPLTIA-------APAF 213

  Fly   370 RSLLECKMILAIVLAIWFSTSTMAMLEPCLPIWLIQYLKPNKWQLGTVFIPDSVGYFVGTNFFGS 434
            .:||:...|:....:|..:...:||.||.||:|::..:....|.||.||.|.|:.|.|.||....
Frog   214 CALLKDPYIVLAAGSICLTNMVIAMAEPTLPVWMLGTMCTPDWLLGIVFFPASISYLVCTNLLPR 278

  Fly   435 IAYKYGQVKVSCISLLLVGVASILIPSATTVAQLLLPHFALGLGIGVIDAALVPLLATFVDATLA 499
            ::.|.|:...|.:.::|.|::.:.:|.|.....|:.|..|.|:.||::|.::|||:|..||.
Frog   279 LSQKIGRWLCSLLGMVLAGISFLCVPLAVNFYGLITPIAAFGISIGMVDVSMVPLMAYLVDL--- 340

  Fly   500 QEDQGEGSSSMSSYGTVYAIQQTSVSLAYCLAPLIGGELAQTFGFAWLMRIVGIFNMIYGPILVY 564
                    ...|.||.||||...:::|.:.:.|.:.|..|:..|..|||.|:.:.|::|.|:.:.
Frog   341 --------RHSSVYGGVYAISDIALNLGFAVGPCVAGITAKAIGLPWLMVIIAVLNIMYSPLCIL 397

  Fly   565 L 565
            |
Frog   398 L 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
prt	NP_001097887.1	MFS	212..565	CDD:119392	126/358 (35%)
prt	NP_001097887.1	MFS_1	212..532	CDD:284993	115/325 (35%)
LOC101731380	XP_031755164.1	MFS_SLC18A1_2_VAT1_2	54..399	CDD:340942	129/363 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	118	1.000	Domainoid score	I5824
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59108
OrthoDB	1	1.010	-	-		D1371520at2759
OrthoFinder	1	1.000	-	-		FOG0000700
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23506
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.030