Protein Alignment HBS1 and Gspt2

DIOPT Version :9

• Sequence 1: NP_001286906.1
• Gene: HBS1 / 117365
• FlyBaseID: FBgn0042712
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_001102789.1
• Gene: Gspt2 / 501582
• RGDID: 1563213
• Length: 632
• Species: Rattus norvegicus
• Alignment Length: 632
• Identity: 201/632 - (31%)
• Similarity: 329/632 - (52%)
• Gaps: 82/632 - (12%)

  Fly    90 PQLDEIEQAKLSSCVDEVRSVVGDAVSERRIVETSMKFDYDMQKILDEILNEETNKSAKPAVNKM 154
            |..|||..|..::      :...:|.::||  ..|:.|            :.:.|.:|||.|..:
  Rat    26 PSGDEIAPAATAA------AEAAEAEAQRR--HLSLAF------------SSQLNINAKPFVPSV 70

  Fly   155 KAPAAPVLPKTVSKTVPTPPPKIS---------LKEPR-RGFEIPSPKVPS--SPVVS--GRNTP 205
            .  ||..:|..:..:...|.|..|         ..||: :..|..:|..||  .|:||  |.|:.
  Rat    71 S--AAEFVPSFLPGSAQLPAPTASSCDETCIGGAAEPQGKRMEWGAPVEPSKDGPLVSWEGSNSA 133

  Fly   206 VDISAGDDISRS---------SATVFKVS-----------------------KEQAVRNARQLYE 238
            |.:...:.:..:         |..:.:||                       :::.:|.::.:..
  Rat   134 VTMELSEPVVENGEVEMALEESWELKEVSEAAPEGSLGDVGPPEESGKEVMEEKEEIRKSKSVVR 198

  Fly   239 KERADQKSHIHMIVIGHVDAGKSTLMGHLLYDTGNVSQRVMHKHEQESKKLGKQSFMYAWVLDET 303
            ...|.:|.|::::.||||||||||:.|.:::.||.|.:|.:.|:|:|:|:..::::..:|.||..
  Rat   199 PSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDRRTLEKYEREAKEKNRETWYLSWALDTN 263

  Fly   304 GEERARGITMDVGQSRIETKTKIVTLLDAPGHKDFIPNMISGATQADVALLVVDATRGEFESGFE 368
            .|||.:|.|::||::..||:.|..|:|||||||.|:||||.||:|||:|:||:.|.:||||:|||
  Rat   264 QEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFE 328

  Fly   369 LGGQTREHAILVRSLGVNQLGVVINKLD--TVGWSQDRFTEIVTKLKSFLKLAGFK-DSDVSFTP 430
            .||||||||:|.::.||..|.|:|||:|  ||.||.:|:.|...||..|||..||. ..|:.|.|
  Rat   329 KGGQTREHAMLAKTAGVKYLIVLINKMDDPTVDWSSERYEECKEKLVPFLKKVGFSPKKDIHFMP 393

  Fly   431 CSGLTGENLTKKAQEPALTNWYSGRHL---LDVIENFKIPERAIDRPLRMSVSDIYKGTGSGFCI 492
            ||||||.|:.:::.   ...||:|...   ||.:.||   .|:||.|:|:.:.|.||..|:  .:
  Rat   394 CSGLTGANIKEQSD---FCPWYTGLPFIPYLDSLPNF---NRSIDGPIRLPIVDKYKDMGT--VV 450

  Fly   493 SGRVETGVLCLNDKVLVGASREQAQVKSLTMNEFPQTCVFAGDQVSVTLPALDINNVTVGCIISD 557
            .|::|:|.:....::::..::...:|..:..::.....|..|:.:.:.|..::...:..|.|:.:
  Rat   451 LGKLESGSIFKGQQLVMMPNKHSVEVLGIVSDDAETDFVAPGENLKIRLKGIEEEEILPGFILCE 515

  Fly   558 PQTPIPVTTRFQARIIVFNVKVPITMGFPVLLHHQSLIEPAVVCKLTASIHKSTGEVVKKKPRCL 622
            |.........|..:|::...|..|..|:..:||..:.||...:..|.:.:.|.:||..|.:||.:
  Rat   516 PNNLCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFV 580

  Fly   623 GNNSCALVELETSRPICIERYADFKELGRVMLRVAGVTIAAGMVTKI 669
            ..:...:..|.|:..||:|.:.||.::||..||..|.|||.|.|.|:
  Rat   581 KQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKL 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HBS1	NP_001286906.1	HBS1_N	83..145	CDD:286079	10/54 (19%)
		TEF1	241..669	CDD:227581	163/433 (38%)
		EF1_alpha	249..468	CDD:206670	108/224 (48%)
		HBS1-like_II	474..557	CDD:293912	15/82 (18%)
		HBS1_C_III	561..669	CDD:294008	33/107 (31%)
Gspt2	NP_001102789.1	PAM2	54..71	CDD:284542	6/28 (21%)
		TEF1	205..629	CDD:227581	163/431 (38%)
		EF1_alpha	209..425	CDD:206670	106/218 (49%)
		eRF3_II	434..514	CDD:293906	15/81 (19%)
		eRF3_C_III	521..627	CDD:294003	33/105 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5256
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1150082at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820