Protein Alignment HBS1 and mIF2

DIOPT Version :10

• Sequence 1: NP_652729.2
• Gene: HBS1 / 117365
• FlyBaseID: FBgn0042712
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_651621.2
• Gene: mIF2 / 43382
• FlyBaseID: FBgn0039588
• Length: 696
• Species: Drosophila melanogaster
• Alignment Length: 482
• Identity: 105/482 - (21%)
• Similarity: 170/482 - (35%)
• Gaps: 124/482 - (25%)

  Fly    75 AAFAKARRDSESFQMPQLDEIEQAKLSSCVDEVRSVVGDAVSERRIVETSMKFDYDMQKILDEIL 139
            ||..|.|:.:|..:.|::.|....|..:        .|...|:.....|..:...::::.||::
  Fly    37 AARLKRRKTAEEKKSPRIIEYSPKKFQT--------AGGGASDIWRHMTVAQLAKELERSLDDV- 92

  Fly   140 NEETNKSAKPAVN---KMKAPAAPVLPKTVSK------TVPTPPPKISLKEPRRGFEIPSPKVPS 195
             :|.....|.|.|   ..|.....::.:...|      .|.||....:.::..|..   :|:.|:
  Fly    93 -QEAMLYVKGADNIEPAFKLADLKIIQEIAKKLGAKTRVVATPEETNADEQKERDV---APRPPA 153

  Fly   196 SPVVSGRNTPVDISAGDDISRSSATVFKVSKEQAVRNARQLYEKERADQKSHIHMIVIGHVDAGK 260
            :|.:.....||                                           :.|:||||.||
  Fly   154 APELLQPRPPV-------------------------------------------VTVMGHVDHGK 175

  Fly   261 STLMGHLLYDTGNVSQRVMHKHEQESKKLGKQSFMYAWVLDETGEERARGITMDVGQSRIETKT- 324
            :||:..|  ...:|:                           .||  |.|||..:|...:..:.
  Fly   176 TTLLDSL--RGADVA---------------------------AGE--AGGITQHIGAFTVTLENG 209

  Fly   325 KIVTLLDAPGHKDFIPNMISGATQADVALLVVDATRGEFESGFELGGQTREHAILVRSLGVNQLG 389
            :.||.||.|||..|......||...|:.:|||.|..|       :..||||...|.:...| .:.
  Fly   210 ERVTFLDTPGHAAFSAMRARGAVATDIIVLVVAAEDG-------VMAQTREVIQLAKEAQV-PII 266

  Fly   390 VVINKLDTVGWSQDRFTEIVTKLKSFLKLAGFKDSDVSFTPCSGLTGENLTKKAQEPALTNWYSG 454
            |.:||:|....:.::....:.::...|:..|   .||...|.|.|.|.||...|:..:......|
  Fly   267 VALNKIDKPEANIEKSKRELAQMGLALEEHG---GDVQVIPISALKGTNLELLAEAVSTQATLMG 328

  Fly   455 RHL--LDVIENFKIPERAIDRPLRMSVSDIYKGT---GSGFCISGRVETGVLCLNDKVLVGASRE 514
            ...  ..::|...:..:...|..::|.:.:.:||   || ..:||.....|..|.|.  .|....
  Fly   329 LKADPTGLVEGIVVESKTDPRRGKLSTAIVSRGTLRKGS-VLLSGLAHAKVRGLFDH--NGQPLS 390

  Fly   515 QA----QVKSLTMNEFPQTCVFAGDQV 537
            :|    .|:.|...|.|    .|||.:
  Fly   391 EAPPGTPVEILGWRELP----LAGDLI 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HBS1	NP_652729.2	HBS1_N	83..148	CDD:462642	10/64 (16%)
		TEF1	242..669	CDD:444074	77/306 (25%)
mIF2	NP_651621.2	InfB	159..688	CDD:440298	79/347 (23%)