DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HBS1 and CG33158

DIOPT Version :9

Sequence 1:	NP_001286906.1	Gene:	HBS1 / 117365	FlyBaseID:	FBgn0042712	Length:	670	Species:	Drosophila melanogaster
Sequence 2:	NP_788515.1	Gene:	CG33158 / 39834	FlyBaseID:	FBgn0053158	Length:	1033	Species:	Drosophila melanogaster

Alignment Length:	315	Identity:	75/315 - (23%)
Similarity:	115/315 - (36%)	Gaps:	110/315 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   197 PVVSGRNTPVDISAGDDISRSSATVFKVSKEQAVRNARQLYEKERADQKSHIHMIVIGHVDAGKS 261
            |||.|                |..|....:.|.|||                 :.::.|||.||:
  Fly     2 PVVEG----------------SDLVLLQRRRQQVRN-----------------ICILAHVDHGKT 33

  Fly   262 TLMGHLLYDTGNVSQRVMHKHEQESKKLGKQSFMYAWVLDETGEERARGITM---------DVGQ 317
            ||...|:...|.:|||:          .||..:     ||...:|:.|||||         ...:
  Fly    34 TLADSLVASNGIISQRM----------AGKLRY-----LDNRSDEQERGITMKSSSISLYYQEAE 83

  Fly   318 SRIETKTKIVTLLDAPGHKDFIPNMISGATQADVALLVVDATRGEFESGFELGGQTREHAILVRS 382
            ........::.|:|:|||.||...:.:.....|.|::|||...|       :|.|||   ..:|.
  Fly    84 EMAGNPDYLINLIDSPGHVDFSSEVSTAVRLCDGAIVVVDVVEG-------VGPQTR---ACLRQ 138

  Fly   383 LGVNQLG--VVINKLDTVGWSQ-----DRFTEIVTKLKSFLKLAG-FKDSDVSFTPCSGLTGENL 439
            :...||.  :|:||||.:...:     |.:..:...|:....:.| ...||:       |..|::
  Fly   139 IYEEQLKPVLVLNKLDRLILEKQMDPLDAYFHLCQVLEQVNAVLGSIFASDI-------LAKEDI 196

  Fly   440 TKKAQEPALTNWYSGRHLLDVIENFKIPERAIDRPLRMSVSDIYKGTGSG---FC 491
            |||                   :|::.....:|.      |::|....||   ||
  Fly   197 TKK-------------------DNYESALEEVDD------SELYFSPSSGNVIFC 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HBS1	NP_001286906.1	HBS1_N	83..145	CDD:286079
		TEF1	241..669	CDD:227581	65/271 (24%)
		EF1_alpha	249..468	CDD:206670	58/235 (25%)
		HBS1-like_II	474..557	CDD:293912	6/21 (29%)
		HBS1_C_III	561..669	CDD:294008
CG33158	NP_788515.1	PTZ00416	15..1016	CDD:240409	69/286 (24%)
		EF2	20..249	CDD:206672	67/281 (24%)
		EF2_II	485..572	CDD:293913
		EF2_snRNP_III	587..658	CDD:293918
		aeEF2_snRNP_like_IV	658..899	CDD:238839
		eEF2_snRNP_like_C	896..974	CDD:239763
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464648
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840