Protein Alignment HBS1 and Gspt1

DIOPT Version :9

• Sequence 1: NP_001286906.1
• Gene: HBS1 / 117365
• FlyBaseID: FBgn0042712
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_001003978.1
• Gene: Gspt1 / 24420
• RGDID: 2751
• Length: 636
• Species: Rattus norvegicus
• Alignment Length: 588
• Identity: 188/588 - (31%)
• Similarity: 299/588 - (50%)
• Gaps: 68/588 - (11%)

  Fly   135 LDEILNEETNKSAKPAV----------NKMKAPAAPVLPKTVSKTVPTPPPKISLKEPRRGFEIP 189
            |....:.:.|.:|||.|          :.::.||.|          |..|...:..:...|....
  Rat    59 LSAAFSRQLNVNAKPFVPNVHAAEFVPSFLRGPAQP----------PLSPAGAAGGDHGAGSSAG 113

  Fly   190 SPKVP---------------------SSPVVSGRNTPVDI-------------------SAGDDI 214
            .|..|                     |.|||....|.:..                   |:||..
  Rat   114 GPSEPVESSQEQSLCEGSNSTVSMELSEPVVENGETEMSPEESWEHKEEISEAEPAGGGSSGDGR 178

  Fly   215 SRSSATVFKVSKEQAVRNARQLYEKERADQKSHIHMIVIGHVDAGKSTLMGHLLYDTGNVSQRVM 279
            ....:|...:.:|:.:...:.:.....|.:|.|::::.||||||||||:.|.::|.||.|.:|.:
  Rat   179 PPEESTQEMMEEEEEIPKPKSVVAPPGAPKKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTL 243

  Fly   280 HKHEQESKKLGKQSFMYAWVLDETGEERARGITMDVGQSRIETKTKIVTLLDAPGHKDFIPNMIS 344
            .|:|:|:|:..::::..:|.||...|||.:|.|::||::..||:.|..|:|||||||.|:||||.
  Rat   244 EKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIG 308

  Fly   345 GATQADVALLVVDATRGEFESGFELGGQTREHAILVRSLGVNQLGVVINKLD--TVGWSQDRFTE 407
            ||:|||:|:||:.|.:||||:|||.||||||||:|.::.||..|.|:|||:|  ||.||.:|:.|
  Rat   309 GASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSNERYEE 373

  Fly   408 IVTKLKSFLKLAGFK-DSDVSFTPCSGLTGENLTKKAQEPALTNWYSGRHLLDVIENFKIPERAI 471
            ...||..|||..||. ..|:.|.|||||||.||.:::.   ...||.|...:..::|.....|::
  Rat   374 CKEKLIPFLKKVGFNPKKDIHFMPCSGLTGANLKEQSD---FCPWYIGLPFIPYLDNLPNFNRSV 435

  Fly   472 DRPLRMSVSDIYKGTGSGFCISGRVETGVLCLNDKVLVGASREQAQVKSLTMNEFPQTCVFAGDQ 536
            |.|:|:.:.|.||..|:  .:.|::|:|.:|...::::..::...:|..:..::.....|..|:.
  Rat   436 DGPIRLPIVDKYKDMGT--VVLGKLESGSICKGQQLVMMPNKHNVEVLGILSDDVETDSVAPGEN 498

  Fly   537 VSVTLPALDINNVTVGCIISDPQTPIPVTTRFQARIIVFNVKVPITMGFPVLLHHQSLIEPAVVC 601
            :.:.|..::...:..|.|:.|..........|.|:|::...|..|..|:..:||..:.||...:.
  Rat   499 LKIRLKGIEEEEILPGFILCDLNNLCHSGRTFDAQIVIIEHKSIICPGYNAVLHIHTCIEEVEIT 563

  Fly   602 KLTASIHKSTGEVVKKKPRCLGNNSCALVELETSRPICIERYADFKELGRVMLRVAGVTIAAGMV 666
            .|...:.|.:||..|.:||.:..:...:..|.|:..||:|.:.||.::||..||..|.|||.|.|
  Rat   564 ALICLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKV 628

  Fly   667 TKI 669
            .|:
  Rat   629 LKL 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HBS1	NP_001286906.1	HBS1_N	83..145	CDD:286079	1/9 (11%)
		TEF1	241..669	CDD:227581	163/430 (38%)
		EF1_alpha	249..468	CDD:206670	107/221 (48%)
		HBS1-like_II	474..557	CDD:293912	16/82 (20%)
		HBS1_C_III	561..669	CDD:294008	34/107 (32%)
Gspt1	NP_001003978.1	PAM2	62..79	CDD:284542	5/16 (31%)
		TEF1	209..633	CDD:227581	163/428 (38%)
		EF1_alpha	213..429	CDD:206670	107/218 (49%)
		eRF3_II	438..519	CDD:293906	16/82 (20%)
		eRF3_C_III	525..631	CDD:294003	34/105 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5256
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1150082at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820