Protein Alignment HBS1 and Gspt1

DIOPT Version :10

• Sequence 1: NP_652729.2
• Gene: HBS1 / 117365
• FlyBaseID: FBgn0042712
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_001003978.1
• Gene: Gspt1 / 24420
• RGDID: 2751
• Length: 636
• Species: Rattus norvegicus
• Alignment Length: 588
• Identity: 188/588 - (31%)
• Similarity: 299/588 - (50%)
• Gaps: 68/588 - (11%)

  Fly   135 LDEILNEETNKSAKPAV----------NKMKAPAAPVLPKTVSKTVPTPPPKISLKEPRRGFEIP 189
            |....:.:.|.:|||.|          :.::.||.|          |..|...:..:...|....
  Rat    59 LSAAFSRQLNVNAKPFVPNVHAAEFVPSFLRGPAQP----------PLSPAGAAGGDHGAGSSAG 113

  Fly   190 SPKVP---------------------SSPVVSGRNTPVDI-------------------SAGDDI 214
            .|..|                     |.|||....|.:..                   |:||..
  Rat   114 GPSEPVESSQEQSLCEGSNSTVSMELSEPVVENGETEMSPEESWEHKEEISEAEPAGGGSSGDGR 178

  Fly   215 SRSSATVFKVSKEQAVRNARQLYEKERADQKSHIHMIVIGHVDAGKSTLMGHLLYDTGNVSQRVM 279
            ....:|...:.:|:.:...:.:.....|.:|.|::::.||||||||||:.|.::|.||.|.:|.:
  Rat   179 PPEESTQEMMEEEEEIPKPKSVVAPPGAPKKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTL 243

  Fly   280 HKHEQESKKLGKQSFMYAWVLDETGEERARGITMDVGQSRIETKTKIVTLLDAPGHKDFIPNMIS 344
            .|:|:|:|:..::::..:|.||...|||.:|.|::||::..||:.|..|:|||||||.|:||||.
  Rat   244 EKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIG 308

  Fly   345 GATQADVALLVVDATRGEFESGFELGGQTREHAILVRSLGVNQLGVVINKLD--TVGWSQDRFTE 407
            ||:|||:|:||:.|.:||||:|||.||||||||:|.::.||..|.|:|||:|  ||.||.:|:.|
  Rat   309 GASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSNERYEE 373

  Fly   408 IVTKLKSFLKLAGFK-DSDVSFTPCSGLTGENLTKKAQEPALTNWYSGRHLLDVIENFKIPERAI 471
            ...||..|||..||. ..|:.|.|||||||.||.:::.   ...||.|...:..::|.....|::
  Rat   374 CKEKLIPFLKKVGFNPKKDIHFMPCSGLTGANLKEQSD---FCPWYIGLPFIPYLDNLPNFNRSV 435

  Fly   472 DRPLRMSVSDIYKGTGSGFCISGRVETGVLCLNDKVLVGASREQAQVKSLTMNEFPQTCVFAGDQ 536
            |.|:|:.:.|.||..|:  .:.|::|:|.:|...::::..::...:|..:..::.....|..|:.
  Rat   436 DGPIRLPIVDKYKDMGT--VVLGKLESGSICKGQQLVMMPNKHNVEVLGILSDDVETDSVAPGEN 498

  Fly   537 VSVTLPALDINNVTVGCIISDPQTPIPVTTRFQARIIVFNVKVPITMGFPVLLHHQSLIEPAVVC 601
            :.:.|..::...:..|.|:.|..........|.|:|::...|..|..|:..:||..:.||...:.
  Rat   499 LKIRLKGIEEEEILPGFILCDLNNLCHSGRTFDAQIVIIEHKSIICPGYNAVLHIHTCIEEVEIT 563

  Fly   602 KLTASIHKSTGEVVKKKPRCLGNNSCALVELETSRPICIERYADFKELGRVMLRVAGVTIAAGMV 666
            .|...:.|.:||..|.:||.:..:...:..|.|:..||:|.:.||.::||..||..|.|||.|.|
  Rat   564 ALICLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKV 628

  Fly   667 TKI 669
            .|:
  Rat   629 LKL 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HBS1	NP_652729.2	HBS1_N	83..148	CDD:462642	2/12 (17%)
		TEF1	242..669	CDD:444074	163/429 (38%)
Gspt1	NP_001003978.1	PAM2	63..79	CDD:429316	5/15 (33%)
		TEF1	206..635	CDD:444074	164/431 (38%)