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Protein Alignment HBS1 and erfa-3

DIOPT Version :9

Sequence 1:	NP_001286906.1	Gene:	HBS1 / 117365	FlyBaseID:	FBgn0042712	Length:	670	Species:	Drosophila melanogaster
Sequence 2:	NP_001256292.1	Gene:	erfa-3 / 179537	WormBaseID:	WBGene00010405	Length:	532	Species:	Caenorhabditis elegans

Alignment Length:	544	Identity:	192/544 - (35%)
Similarity:	305/544 - (56%)	Gaps:	45/544 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   144 NKSAKPAVNKMKAPAAPVLPKTVSKTVPTPPPKISLKEPRRGFEIPSPKVPSS--PVVSGRNTPV 206
            |.:|:|.|     |..|.          ||.|:.:..||...:|..:...|::  |.|:   .||
Worm    14 NANARPFV-----PGQPY----------TPQPEQAAPEPTEDWEAQADTSPAAVQPEVA---EPV 60

  Fly   207 DISAGDDISRSSATVFKVSKEQ-----------AVRNARQLYEKERADQKSHIHMIVIGHVDAGK 260
            .:.....::..|||  :..|::           |.:..|.:|..: ...|.||:|:.:|||||||
Worm    61 AVQESAPVAPVSAT--EAPKKEPTPEEDLVAPLAKKFQRTVYVDD-GTHKEHINMVFVGHVDAGK 122

  Fly   261 STLMGHLLYDTGNVSQRVMHKHEQESKKLGKQSFMYAWVLDETGEERARGITMDVGQSRIETKTK 325
            ||:.|.|::.||.|.:|.:.|:|:|:|:.|::|:..:|.:|...|||.:|.|::||::..||:.:
Worm   123 STIGGQLMFLTGMVDKRTLEKYEREAKEKGRESWYLSWCMDTNDEEREKGKTVEVGRAYFETEKR 187

  Fly   326 IVTLLDAPGHKDFIPNMISGATQADVALLVVDATRGEFESGFELGGQTREHAILVRSLGVNQLGV 390
            ..|:|||||||.|:||||.||.|||:|:||:.|.|||||:||:.|||||||::||::.||..|.:
Worm   188 HFTILDAPGHKSFVPNMIVGANQADLAVLVISARRGEFETGFDRGGQTREHSMLVKTAGVKHLVI 252

  Fly   391 VINKLD--TVGWSQDRFTEIVTKLKSFLKLAGFK-DSDVSFTPCSGLTGENLTKKAQEPALTNWY 452
            ::||:|  ||.|.::||.||..||..||:..||. .:|:::.|||||||. ..|.....:..|||
Worm   253 LVNKMDDPTVKWEEERFKEIEGKLTPFLRKLGFNPKTDITYVPCSGLTGA-FIKDRPTGSEGNWY 316

  Fly   453 SGRHLLDVIENFKIP--ERAIDRPLRMSVSDIYKGTGSGFCISGRVETGVLCLNDKVLVGASREQ 515
            ||...::.|: ..:|  :|..:.|:|.:|::.|...|:  .|.|::|:|.:...|.::|..:::.
Worm   317 SGPCFIEFID-VLLPSYKRDFNGPVRCTVAEKYSEMGT--VIIGKMESGCVQKGDTLVVMPNKQP 378

  Fly   516 AQVKSLTMNEFPQTCVFAGDQVSVTLPALDINNVTVGCIISDPQTPIPVTTRFQARIIVFNVKVP 580
            .||..:..::.....|.|||.:...|..::.|.:..|.||..|.:.......|.|.::|...:..
Worm   379 VQVLQIWADDVETERVVAGDNIKFKLKGIEENELQGGFIICSPDSLAKTGRVFDAEVLVLEHRSI 443

  Fly   581 ITMGFPVLLHHQSLIEPAVVCKLTASIHKSTGEVVKKKPRCLGNNSCALVELETSRPICIERYAD 645
            |..|:..:||.||.:|...|..:.|:|.|.|||  ||:.:.:..:...::.||:..|..:|.:.:
Worm   444 IASGYSCVLHIQSAVEEVTVKGVIATIDKKTGE--KKRAKFVKQDEKCIMRLESPEPFVLEPFKE 506

  Fly   646 FKELGRVMLRVAGVTIAAGMVTKI 669
            :..|||..||..|.|||.|.|.|:
Worm   507 YPYLGRFTLRDEGKTIAIGKVLKV 530

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.