Protein Alignment Hex-t1 and EMI2

DIOPT Version :10

• Sequence 1: NP_788744.1
• Gene: Hex-t1 / 117364
• FlyBaseID: FBgn0042711
• Length: 465
• Species: Drosophila melanogaster
• Sequence 2: NP_010804.3
• Gene: EMI2 / 852128
• SGDID: S000002924
• Length: 500
• Species: Saccharomyces cerevisiae
• Alignment Length: 460
• Identity: 115/460 - (25%)
• Similarity: 202/460 - (43%)
• Gaps: 84/460 - (18%)

  Fly    53 VPCHLSYVQDLPTGRERGQFLALEMMPTNCRIMLVKFSSE------------RDIYTSSKCVIMP 105
            :|...:||..||.|.|||..||.::..|:.|:..|..:.:            .:.|.:.|.|
Yeast    62 LPMIPTYVTSLPNGTERGVLLAADLGGTHFRVCSVTLNGDGTFDMQQLKSKIPEEYLNDKDV--- 123

  Fly   106 HTVAAGRGTEVFTFLATSIANFVKEK-----KVDKDN---LPLGIAFAFTLKKLALDVGILVSWT 162
                  ...|:|::|......||::.     |...:|   |.:|..|::.:.:.:|..|.|:.||
Yeast   124 ------TSEELFSYLGRRTRAFVRKHHPELLKSTGENIKPLKMGFTFSYPVDQTSLSSGTLIRWT 182

  Fly   163 KEFGAQGAIGKDVVQLLRDALAKFPEISVDVMGI--INVGA------GSLLALCW---AQPDTR- 215
            |.|..:..:|||||:|.::.|        |:.|:  |||.|      |:.|:.|:   ::|.:.
Yeast   183 KSFKIEDTVGKDVVRLYQEQL--------DIQGLSMINVVALTNDTVGTFLSHCYTSGSRPSSAG 239

  Fly   216 ------IGLIMGSIANSCYVERVERCETYEGD-------EYRKLMIINSDWAHFGDTGQLDFIRN 267
                  ||.|.|:..|.||:|.:|..:....:       |.:..|.||.:|..| |.........
Yeast   240 EISEPVIGCIFGTGTNGCYMEDIENIKKLPDELRTRLLHEGKTQMCINIEWGSF-DNELKHLSAT 303

  Fly   268 EYDRQLDTE-SINPGTRIYEKFSGALCMGELVRIIVLRLMKSGAIFAEDRRDYIGIQWKL----- 326
            :||..:|.: |.|||..::||....:.:|||:|.|::.|...|.|..: .|:|..:..:|
Yeast   304 KYDIDIDQKFSPNPGYHLFEKRISGMYLGELLRNILVDLHARGLILGQ-YRNYDQLPHRLKTPFQ 367

  Fly   327 ---DMVSLIEIVSDPPGVYTKAQEVMDKFRIRHCKERDLAALKYICDTVTNRAAMLVASGVSCL- 387
               :::|.||| .|...:.......:...|:....| :..|::.:..::|.|:|.|.|..::.:
Yeast   368 LCSEVLSRIEI-DDSTNLRETELSFLQSLRLPTTFE-ERKAIQNLVRSITRRSAYLAAVPIAAIL 430

  Fly   388 -----IDRMRLPQISIAVDGGIYRLHPTFSTVLNKYTRLL---ADPNYNFEFVITQDSCGVGAAI 444
                 :::....::.|..||.:...:|.|.::|.....|.   .:........:.:|..|||||:
Yeast   431 IKTNALNKRYHGEVEIGFDGYVIEYYPGFRSMLRHALALSPIGTEGERKIHLRLAKDGSGVGAAL 495

  Fly   445 MAGMA 449
            .|.:|
Yeast   496 CALVA 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hex-t1	NP_788744.1	ASKHA_ATPase-like	24..446	CDD:483947	113/455 (25%)
EMI2	NP_010804.3	ASKHA_NBD_GLK1-2_fungi	29..497	CDD:466938	113/455 (25%)