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Protein Alignment Hex-t1 and HKDC1

DIOPT Version :9

Sequence 1:	NP_788744.1	Gene:	Hex-t1 / 117364	FlyBaseID:	FBgn0042711	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_079406.4	Gene:	HKDC1 / 80201	HGNCID:	23302	Length:	917	Species:	Homo sapiens

Alignment Length:	444	Identity:	144/444 - (32%)
Similarity:	249/444 - (56%)	Gaps:	12/444 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 EVYKVCKLFNPSIDDLEKIKNAMDREITMGLSRDHHDRSTVPCHLSYVQDLPTGRERGQFLALEM 77
            ::.:|..||..:.:.|..::..|..|:..||.:..|..:||....:||..||.|.|:|:||||::
Human   469 QIDRVLALFQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDL 533

  Fly    78 MPTNCRIMLVKF-SSERDIYTSSKCVIMPHTVAAGRGTEVFTFLATSIANFVKEKKVDKDNLPLG 141
            ..||.|::|||. |..|.:...:|...:|..:..|.|.|:|..:...||:|:....:...:||||
Human   534 GGTNFRVLLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLG 598

  Fly   142 IAFAFTLKKLALDVGILVSWTKEFGAQGAIGKDVVQLLRDALAKFPEISVDVMGIINVGAGSLLA 206
            ..|:|..:::::|.|.|:.|||.|.|....|:|||.:||:|:.:..|..:|::.::|...|:::.
Human   599 FTFSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGTMMT 663

  Fly   207 LCWAQPDTRIGLIMGSIANSCYVERVERCETYEGDEYRKLMIINSDWAHFGDTGQLDFIRNEYDR 271
            ..:..|:..||||.|:.:|.||:|.:...|..||.|.:  |.||::|..|||.|.:|.|...||.
Human   664 CGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGGEGK--MCINTEWGGFGDNGCIDDIWTRYDT 726

  Fly   272 QLDTESINPGTRIYEKFSGALCMGELVRIIVLRLMKSGAIFAEDRRDYIGIQWKLDMVSLIEIVS 336
            ::|..|:|||.:.|||.:..:.:||:||.|::.|.|.|.:|.....:.:..:...:...|.:|.|
Human   727 EVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGIFETKFLSQIES 791

  Fly   337 DPPGVYTKAQEVMDKFRIRHCKERDLAALKYICDTVTNRAAMLVASGVSCLIDRMRLPQ------ 395
            |...: .:.:.::.:..:....| |...:|.:|..|:.|||.|..:|::.::::.|..|
Human   792 DRLAL-LQVRRILQQLGLDSTCE-DSIVVKEVCGAVSRRAAQLCGAGLAAIVEKRREDQGLEHLR 854

  Fly   396 ISIAVDGGIYRLHPTFSTVLNKYTRLLADPNYNFEFVITQDSCGVGAAIMAGMA 449
            |::.|||.:|:|||.||.:|.:..:.|| |..:..|::::|..|.|||::..:|
Human   855 ITVGVDGTLYKLHPHFSRILQETVKELA-PRCDVTFMLSEDGSGKGAALITAVA 907

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.