Protein Alignment Hex-t1 and hxk-2

DIOPT Version :9

• Sequence 1: NP_788744.1
• Gene: Hex-t1 / 117364
• FlyBaseID: FBgn0042711
• Length: 465
• Species: Drosophila melanogaster
• Sequence 2: NP_492905.1
• Gene: hxk-2 / 173022
• WormBaseID: WBGene00010416
• Length: 552
• Species: Caenorhabditis elegans
• Alignment Length: 474
• Identity: 150/474 - (31%)
• Similarity: 261/474 - (55%)
• Gaps: 26/474 - (5%)

  Fly     1 MANTFNPEE-DFPEVYKVCKLFNPSIDD-LEKIKNAMDREITMGLSRDHHDRSTVPCHLSYVQDL 63
            ||:..|.|. ....|....||.|.::.. :..:.:.|||.:..||     :|||:....|:|.:|
 Worm    36 MASKLNEESISLESVMAEFKLSNTTLRRMMSHLSDNMDRGLESGL-----ERSTIAMLPSFVPEL 95

  Fly    64 PTGRERGQFLALEMMPTNCRIMLVKFSSERDIYTSSKCVIMPHTVAAGRGTEVFTFLATSIANFV 128
            |.|:|||:|:|:::..||.|:||::......:.|......||:....|.|.::|.::|.::.:|:
 Worm    96 PNGKERGKFVAMDLGGTNLRVMLMELEPGEPMRTKQFNTRMPNAAMHGTGQKLFDYIAKALCDFL 160

  Fly   129 KEKKVDKDNLPLGIAFAFTLKKLALDVGILVSWTKEFGAQGAIGKDVVQLLRDALAKFPEISVDV 193
            .|:::..::||:|..|::...:..|....|:.|||...|.|.:|:||||||.||:|:...:.|::
 Worm   161 VERELADEHLPVGFTFSYPCDQTGLRSATLLRWTKGVTATGCVGEDVVQLLEDAIARDGRVKVNI 225

  Fly   194 MGIINVGAGSLLALCW-AQPDTRIGLIMGSIANSCYVER----VERCETYEGDEYRKLMIINSDW 253
            :.:||...|:::|..: |.....||:|:|:..|:.|:|.    |........|...|.|||:::|
 Worm   226 VALINDTVGTMVAAAYEAGGHCDIGVIIGTGTNASYMEDSRKIVHGLANATEDYNHKSMIIDTEW 290

  Fly   254 AHFGDTGQLDFIRNEYDRQLDTESINPGTRIYEKFSGALCMGELVRIIVLRLMKSGAIFAEDRRD 318
            ..|||.|:.|:|...||:.:|::|.:||....:|....:|||||||:::.||.::..:|.
 Worm   291 GGFGDNGEADYIFTRYDKIVDSKSDHPGVNSLDKLIAGMCMGELVRLVLERLCENKVLFN----- 350

  Fly   319 YIGIQWKL-------DMVSLIEIVSDPPGVYTKAQEVMDKFRIRHCKERDLAALKYICDTVTNRA 376
              ||..|:       ....:.||:.|..|||:..:::||:..|......|:..|:.:|..|:.|:
 Worm   351 --GIGSKMLRTRNTFPTKYISEILHDDCGVYSNTRQIMDELGIEGATFSDMLLLREVCVVVSRRS 413

  Fly   377 AMLVASGVSCLIDRMRLPQISIAVDGGIYRLHPTFSTVLNKYTRLLADPNYNFEFVITQDSCGVG 441
            |.|.|:.::|:::|:|.|.:.:|:||..|:.||.|:..:.:..|.|.||..:|:.|.|.|..|.|
 Worm   414 ANLAAAAIACVLNRVRRPNMLVAIDGSTYKYHPFFNHWVCEKIRELLDPGLDFKIVQTGDGSGRG 478

  Fly   442 AAIMAGMAHANKYKTDAKL 460
            ||::|.:....|.:.:.:|
 Worm   479 AALIAAIVSRVKREEEKRL 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hex-t1	NP_788744.1	COG5026	13..446	CDD:227359	143/445 (32%)
		Hexokinase_1	13..209	CDD:278764	62/196 (32%)
		Hexokinase_2	215..448	CDD:281689	81/243 (33%)
hxk-2	NP_492905.1	PTZ00107	41..487	CDD:240270	146/457 (32%)
		Hexokinase_1	47..241	CDD:278764	62/198 (31%)
		Hexokinase_2	249..485	CDD:281689	81/242 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5026
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1223
OMA	1	1.010	-	-		QHG56451
OrthoDB	1	1.010	-	-		D1153545at2759
OrthoFinder	1	1.000	-	-		FOG0000301
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19443
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X170
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.880