Protein Alignment Hex-t1 and hxk-1

DIOPT Version :9

• Sequence 1: NP_788744.1
• Gene: Hex-t1 / 117364
• FlyBaseID: FBgn0042711
• Length: 465
• Species: Drosophila melanogaster
• Sequence 2: NP_001021106.1
• Gene: hxk-1 / 172751
• WormBaseID: WBGene00008780
• Length: 500
• Species: Caenorhabditis elegans
• Alignment Length: 446
• Identity: 146/446 - (32%)
• Similarity: 247/446 - (55%)
• Gaps: 13/446 - (2%)

  Fly    14 VYKVCKLFNPSIDDLEKIKNAMDREITMGLSRDHHDRSTVPCHLSYVQDLPTGRERGQFLALEMM 78
            :.:.|:....|...|.:|..:|::.:..||:.. ..:..|....:||..:|.|.|.|.||||::.
 Worm    39 IQEACQRLVLSDQQLRRIMQSMEKSMEQGLATS-TKKVAVKMLPTYVDSVPNGTESGDFLALDLG 102

  Fly    79 PTNCRIMLVKFSSERDIYTSSKCVIMPHTVAAGRGTEVFTFLATSIANFVKEKKV-DKDNLPLGI 142
            .||.|::.:|... ::...:.|...:|.::..|.|..:|..:|..:|.|:.|..: |...||||.
 Worm   103 GTNFRVLHIKLQG-KETKMTGKIFRVPESIMRGTGEALFDHIAGCMAKFMGENDLKDAQKLPLGF 166

  Fly   143 AFAFTLKKLALDVGILVSWTKEFGAQGAIGKDVVQLLRDALAKFPEISVDVMGIINVGAGSLLAL 207
            .|:|..::..|..|.||:|||.|.|.|..|.|||.||.:|..:..:|.:||:.::|...|:|:|.
 Worm   167 TFSFPCEQEGLTKGKLVTWTKGFKASGVEGVDVVTLLHEACHRRKDIDIDVVALLNDTVGTLMAC 231

  Fly   208 CWAQPDTRIGLIMGSIANSCYVERVERCETYEG--DEY---RKLMIINSDWAHFGDTGQLDFIRN 267
            .:.:...:||:|:|:..|:||:||::|.....|  ||:   .:.||||::|..|||.|.|||:|.
 Worm   232 AFQENSCQIGVIVGTGTNACYMERLDRIPKLAGYVDEHGVTPEEMIINTEWGAFGDDGALDFLRT 296

  Fly   268 EYDRQLDTESINPGTRIYEKFSGALCMGELVRIIVLRLMKSGAIFAEDRRDYIGIQ--WKLDMVS 330
            |:|..:|.||||||..:|||....:.|||..|:::..|.|.|.:|. ...|.|.:.  :....||
 Worm   297 EWDEVVDRESINPGQHLYEKMISGMYMGECARVVLEDLAKQGLLFG-GNSDAISVPHCFPTKFVS 360

  Fly   331 LI--EIVSDPPGVYTKAQEVMDKFRIRHCKERDLAALKYICDTVTNRAAMLVASGVSCLIDRMRL 393
            .|  :::.|....:.|..::::...:......|.|.:.|:|..::.|||.|.|:|::.|::||..
 Worm   361 EIDSDLLEDDDRTFQKTYQILEDIGVEMITANDCANVAYVCSLISTRAAHLTAAGIAMLLNRMNK 425

  Fly   394 PQISIAVDGGIYRLHPTFSTVLNKYTRLLADPNYNFEFVITQDSCGVGAAIMAGMA 449
            ..:::.|||.:||.|||:.|:|:.....|...:..::.::::|..|.|||::|.:|
 Worm   426 KHVTVGVDGSVYRFHPTYPTLLDAKIGELIVGDIEYKLMLSEDGSGRGAALVAAVA 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hex-t1	NP_788744.1	COG5026	13..446	CDD:227359	144/441 (33%)
		Hexokinase_1	13..209	CDD:278764	62/195 (32%)
		Hexokinase_2	215..448	CDD:281689	83/241 (34%)
hxk-1	NP_001021106.1	COG5026	37..487	CDD:227359	146/446 (33%)
		Hexokinase_1	39..233	CDD:278764	62/195 (32%)
		Hexokinase_2	239..480	CDD:281689	83/241 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159243
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1223
OMA	1	1.010	-	-		QHG56451
OrthoDB	1	1.010	-	-		D1153545at2759
OrthoFinder	1	1.000	-	-		FOG0000301
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19443
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X170
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.910