Protein Alignment Hex-t1 and Gck

DIOPT Version :9

• Sequence 1: NP_788744.1
• Gene: Hex-t1 / 117364
• FlyBaseID: FBgn0042711
• Length: 465
• Species: Drosophila melanogaster
• Sequence 2: XP_006514506.1
• Gene: Gck / 103988
• MGIID: 1270854
• Length: 487
• Species: Mus musculus
• Alignment Length: 413
• Identity: 128/413 - (30%)
• Similarity: 236/413 - (57%)
• Gaps: 18/413 - (4%)

  Fly    14 VYKVCKLFNPSIDDLEKIKNAMDREITMGLSRDHHDRSTVPCHLSYVQDLPTGRERGQFLALEMM 78
            |.::...|....:||:|:.:.|.:|:..||..:.|..::|....:||:..|.|.|.|.||:|::.
Mouse    16 VEQILAEFQLQEEDLKKVMSRMQKEMDRGLKLETHQEASVKMLPTYVRSTPEGSEVGDFLSLDLG 80

  Fly    79 PTNCRIMLVKF----SSERDIYTSSKCVIMPHTVAAGRGTEVFTFLATSIANFVKEKKVDKDNLP 139
            .||.|:||||.    :.:..:.|..:...:|.....|....:|.:::..|::|:.:.::....||
Mouse    81 GTNFRVMLVKVGEGEAGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKKLP 145

  Fly   140 LGIAFAFTLKKLALDVGILVSWTKEFGAQGAIGKDVVQLLRDALAKFPEISVDVMGIINVGAGSL 204
            ||..|:|.::...:|.|||::|||.|.|.||.|.::|.|||||:.:..:..:||:.::|....::
Mouse   146 LGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNIVGLLRDAIKRRGDFEMDVVAMVNDTVATM 210

  Fly   205 LALCWAQPDTRIGLIMGSIANSCYVERVERCETYEGDEYRKLMIINSDWAHFGDTGQLDFIRNEY 269
            ::..:......:|:|:|:..|:||:|.::..|..||||.|  |.:|::|..||::|:||....||
Mouse   211 ISCYYEDRQCEVGMIVGTGCNACYMEEMQNVELVEGDEGR--MCVNTEWGAFGNSGELDEFLLEY 273

  Fly   270 DRQLDTESINPGTRIYEKFSGALCMGELVRIIVLRLMKSGAIFAEDRRDYIGIQWKLDMVSLIEI 334
            ||.:|..|:|||.::|||..|...||||||:::|:|::...:|..:..:.:..:...:...:.::
Mouse   274 DRMVDESSVNPGQQLYEKIIGGKYMGELVRLVLLKLVEENLLFHGEASEQLRTRGAFETRFVSQV 338

  Fly   335 VSDPPGVYTKAQEVMDKFRIRHCKERDLAALKYICDTVTNRAAMLVASGVSCLIDRMR------L 393
            .|| .|...:...::....:|. ...|...::..|::|:.|||.:.::|::.:|:|||      :
Mouse   339 ESD-SGDRRQILNILSTLGLRP-SVADCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDV 401

  Fly   394 PQISIAVDGGIYRLHP----TFS 412
            .:|::.|||.:|:|||    ||:
Mouse   402 MRITVGVDGSVYKLHPRSASTFA 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hex-t1	NP_788744.1	COG5026	13..446	CDD:227359	128/413 (31%)
		Hexokinase_1	13..209	CDD:278764	60/198 (30%)
		Hexokinase_2	215..448	CDD:281689	68/208 (33%)
Gck	XP_006514506.1	COG5026	16..418	CDD:227359	125/405 (31%)
		Hexokinase_1	16..215	CDD:376323	60/198 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5026
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1223
OMA	1	1.010	-	-		QHG56451
OrthoDB	1	1.010	-	-		D1153545at2759
OrthoFinder	1	1.000	-	-		FOG0000301
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19443
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X170
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.840