DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pcyt1 and Pcyt1b

DIOPT Version :9

Sequence 1:	NP_001261264.1	Gene:	Pcyt1 / 117353	FlyBaseID:	FBgn0041342	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_775174.2	Gene:	Pcyt1b / 286936	RGDID:	708434	Length:	369	Species:	Rattus norvegicus

Alignment Length:	361	Identity:	174/361 - (48%)
Similarity:	225/361 - (62%)	Gaps:	45/361 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   166 TICKPAPYSHDEEAMLERDRCDYTQRITYQMARSG-QTTRRVRVYADGIYDLFHQGHARQLMQAK 229
            |:..|||::.:.....:...    :::|...||.| ...|.||||||||:||||.||||.|||||
  Rat    40 TLTAPAPFADESSCQCQAPH----EKLTIAQARLGTPVDRPVRVYADGIFDLFHSGHARALMQAK 100

  Fly   230 NIFPNVYLIVGVCNDELTHRMKGRTVMNGFERYEGVRHCRYVDEIVQNAPWTLSDEFIADNKIDF 294
            .:|||.||:||||:|:|||:.||.||||..||||.:||||||||::::|||||:.||:..:||||
  Rat   101 TLFPNSYLLVGVCSDDLTHKFKGFTVMNEAERYEALRHCRYVDEVIRDAPWTLTPEFLEKHKIDF 165

  Fly   295 VAHDDIPYVTDGMDDIYAPLKARGMFVATERTEGVSTSDIVARIVKDYDLYVRRNLARGYSAKEL 359
            ||||||||.:.|.||:|..:|..||||.|:||||:|||||:.|||:|||:|.||||.|||:||||
  Rat   166 VAHDDIPYSSAGSDDVYKHIKEAGMFVPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKEL 230

  Fly   360 NVSFLSEKKFRLQNKMDELKSRGK--RELSKVKV--------DIITKWEEKSREFIDTFLLLFGR 414
            ||||::|||:|.||::|::|.:.|  .|.||..|        |:|.||||||||||..||.|||.
  Rat   231 NVSFINEKKYRFQNQVDKMKEKVKNVEERSKEFVNRVEEKSHDLIQKWEEKSREFIGNFLELFGP 295

  Fly   415 ENL-NHLWNESKGKLLQALSPPGSPSGSVNGDDTEGGEDYSETIDEYLEMAEKLSGGSGSGSSGS 478
            :.. ..::.|...::||||||..||..|                    ....:....|.|.:...
  Rat   296 DGAWKQMFQERSSRMLQALSPKQSPVSS--------------------PTRSRSPSRSPSPTFSW 340

  Fly   479 LNGKQRPKQKRSSLARRSYQSLQSQSPDLEADGDED 514
            |..|..|    .|..:.:..|:.|.|     :||||
  Rat   341 LPNKTSP----PSSPKAASASISSMS-----EGDED 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pcyt1	NP_001261264.1	PLN02413	202..462	CDD:215229	153/270 (57%)
Pcyt1	NP_001261264.1	CCT	204..353	CDD:173925	102/148 (69%)
Pcyt1b	NP_775174.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..27
		PLN02413	72..314	CDD:215229	146/241 (61%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	309..369		22/88 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340082
Domainoid	1	1.000	204	1.000	Domainoid score	I2847
eggNOG	1	0.900	-	-		E1_COG0615
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	331	1.000	Inparanoid score	I2350
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1172502at2759
OrthoFinder	1	1.000	-	-		FOG0001344
OrthoInspector	1	1.000	-	-		mtm9063
orthoMCL	1	0.900	-	-		OOG6_101770
Panther	1	1.100	-	-	O	PTHR10739
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X834
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.760