DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pcyt1 and pcyt1ba

DIOPT Version :9

Sequence 1:	NP_001261264.1	Gene:	Pcyt1 / 117353	FlyBaseID:	FBgn0041342	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_001076415.1	Gene:	pcyt1ba / 100001552	ZFINID:	ZDB-GENE-061220-4	Length:	343	Species:	Danio rerio

Alignment Length:	364	Identity:	173/364 - (47%)
Similarity:	226/364 - (62%)	Gaps:	51/364 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   166 TICKPAPYSHDEEAMLERDRCDYT---QRITYQMARSG-QTTRRVRVYADGIYDLFHQGHARQLM 226
            |:.:||.::.:..       |:..   :::|...|..| ...|.||||||||:||||.||||.||
Zfish    14 TLIEPAIFTPETS-------CECRAPHEKLTVDQASHGTPVDRPVRVYADGIFDLFHSGHARALM 71

  Fly   227 QAKNIFPNVYLIVGVCNDELTHRMKGRTVMNGFERYEGVRHCRYVDEIVQNAPWTLSDEFIADNK 291
            ||||:|||.|||||||:|||||:.||.|||...||||.:||||||||::::|||||:.:|:..:|
Zfish    72 QAKNLFPNTYLIVGVCSDELTHKYKGFTVMTEDERYEALRHCRYVDEVLRDAPWTLTQDFLEKHK 136

  Fly   292 IDFVAHDDIPYVTDGMDDIYAPLKARGMFVATERTEGVSTSDIVARIVKDYDLYVRRNLARGYSA 356
            |||||||||||.:.|.:|:|..:|..||||.|:||||:||||::.|||:|||:|.||||.|||:|
Zfish   137 IDFVAHDDIPYSSAGSEDVYKHIKEAGMFVPTKRTEGISTSDLITRIVRDYDVYARRNLQRGYTA 201

  Fly   357 KELNVSFLSEKKFRLQNKMDELKS--RGKRELSKVKV--------DIITKWEEKSREFIDTFLLL 411
            ||||||:::|||:||||::|.:|.  |...|.||..|        |:|.||||||||||..||.|
Zfish   202 KELNVSYINEKKYRLQNQVDRMKEKVRTVEEKSKHFVYRVEEKSHDLIQKWEEKSREFIGNFLEL 266

  Fly   412 FGRENL-NHLWNESKGKLLQALSPPGSPSGSVNGDDTEGGEDYSETIDEYLEMAEKLSGGSGSGS 475
            ||.:.. ..::.|..|:::||.||.||||.|...|                        .|.|.|
Zfish   267 FGPDGTWKQMFQERSGRMIQAFSPRGSPSSSPPRD------------------------FSPSRS 307

  Fly   476 SGSLNGKQRPKQKRSSLARRSYQSLQSQSPDLEADGDED 514
            ....:....|:....|..:.:..|:.|.|     :||||
Zfish   308 PSPPSRWAMPRTSPPSSPKGASASISSMS-----EGDED 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pcyt1	NP_001261264.1	PLN02413	202..462	CDD:215229	154/270 (57%)
Pcyt1	NP_001261264.1	CCT	204..353	CDD:173925	101/148 (68%)
pcyt1ba	NP_001076415.1	CCT	49..198	CDD:173925	101/148 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579928
Domainoid	1	1.000	199	1.000	Domainoid score	I3006
eggNOG	1	0.900	-	-		E1_COG0615
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	327	1.000	Inparanoid score	I2448
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1172502at2759
OrthoFinder	1	1.000	-	-		FOG0001344
OrthoInspector	1	1.000	-	-		mtm6570
orthoMCL	1	0.900	-	-		OOG6_101770
Panther	1	1.100	-	-	O	PTHR10739
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R892
SonicParanoid	1	1.000	-	-		X834
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.790