Protein Alignment Rheb and DIRAS3

DIOPT Version :10

• Sequence 1: NP_730950.2
• Gene: Rheb / 117332
• FlyBaseID: FBgn0041191
• Length: 182
• Species: Drosophila melanogaster
• Sequence 2: NP_004666.1
• Gene: DIRAS3 / 9077
• HGNCID: 687
• Length: 229
• Species: Homo sapiens
• Alignment Length: 163
• Identity: 54/163 - (33%)
• Similarity: 85/163 - (52%)
• Gaps: 5/163 - (3%)

  Fly     4 KERHIAMMGYRSVGKSSLCIQFVEGQFVDSYDPTIENTFTKIERVKSQDYIVKLIDTAGQDEYSI 68
            ::..:.::|...||||:|..::..|.|...|.||||||:.::.........:.:.|:...|....
Human    36 RDYRVVVVGTAGVGKSTLLHKWASGNFRHEYLPTIENTYCQLLGCSHGVLSLHITDSKSGDGNRA 100

  Fly    69 FPVQYSMDYHGYVLVYSITSQKSFEVVKIIYEKLLDVMGKKY--VPVVLVGNKI-DLHQERTVST 130
            .........|.:|||||:|.:::.|.:|..||.:..:.|...  .|:||||||. |.|:|  |:.
Human   101 LQRHVIARGHAFVLVYSVTKKETLEELKAFYELICKIKGNNLHKFPIVLVGNKSDDTHRE--VAL 163

  Fly   131 EEGKKLAESWRAAFLETSAKQNESVGDIFHQLL 163
            .:|...|..|..||:|.|||.:.:|.::||.||
Human   164 NDGATCAMEWNCAFMEISAKTDVNVQELFHMLL 196

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rheb	NP_730950.2	RheB	5..182	CDD:206709	54/162 (33%)
DIRAS3	NP_004666.1	P-loop containing Nucleoside Triphosphate Hydrolases	37..200	CDD:476819	54/162 (33%)
		Effector region. /evidence=ECO:0000255	66..74		6/7 (86%)