Protein Alignment Rheb and Rasd2

DIOPT Version :10

• Sequence 1: NP_730950.2
• Gene: Rheb / 117332
• FlyBaseID: FBgn0041191
• Length: 182
• Species: Drosophila melanogaster
• Sequence 2: NP_083458.1
• Gene: Rasd2 / 75141
• MGIID: 1922391
• Length: 266
• Species: Mus musculus
• Alignment Length: 195
• Identity: 59/195 - (30%)
• Similarity: 100/195 - (51%)
• Gaps: 23/195 - (11%)

  Fly     1 MPTKERH-IAMMGYRSVGKSSLCIQFVEGQFVDSYDPTIENTFTKIERVKSQDYIVKLIDTAGQD 64
            :|.|..: :.::|...|||||:..:|:.|:|.|.|.||||:...|:..:....|.:.::||:|..
Mouse    14 VPAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIHGDMYQLDILDTSGNH 78

  Fly    65 EYSIFPVQYSMDY---HGYVLVYSITSQKSFEVVKIIYEKLLDVMG--------KKYVPVVLVGN 118
            .   ||....:..   ..::||:|:.|::||:.||.:.:::|:|..        ...:|:|:.||
Mouse    79 P---FPAMRRLSILTGDVFILVFSLDSRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICGN 140

  Fly   119 KIDLHQE--RTVSTEEGKKLAE-SWRAAFLETSAKQNESVGDIFHQLLILIENENGNPQEKSGCL 180
            |.| |.|  |.|...|.:.|.. ....|:.|.|||:|.:|.::|:.|..:.:    .|.|.|..|
Mouse   141 KND-HSELCRQVPAMEAELLVSGDENCAYFEVSAKKNTNVNEMFYVLFSMAK----LPHEMSPAL 200

  Fly   181  180
            Mouse   201  200

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rheb	NP_730950.2	RheB	5..182	CDD:206709	57/191 (30%)
Rasd2	NP_083458.1	Rhes_like	20..266	CDD:133343	57/189 (30%)
		Effector region	48..56		5/7 (71%)
		Interaction with GNB1, GNB2 and GNB3. /evidence=ECO:0000250	189..235		4/16 (25%)