DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rheb and Diras1

DIOPT Version :9

Sequence 1:	NP_730950.2	Gene:	Rheb / 117332	FlyBaseID:	FBgn0041191	Length:	182	Species:	Drosophila melanogaster
Sequence 2:	NP_001102457.1	Gene:	Diras1 / 366826	RGDID:	1310445	Length:	198	Species:	Rattus norvegicus

Alignment Length:	192	Identity:	63/192 - (32%)
Similarity:	112/192 - (58%)	Gaps:	19/192 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MP--TKERHIAMMGYRSVGKSSLCIQFVEGQFVDSYDPTIENTFTKIERVKSQDYIVKLIDTAGQ 63
            ||  :.:..:.:.|...||||||.::||:|.|.|:|.||||:|:.::.........:::.||.|.
  Rat     1 MPEQSNDYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQITDTTGS 65

  Fly    64 DEYSIFPVQYSMDY---HGYVLVYSITSQKSFEVVKIIYEKLLDVMGK-KYVPVVLVGNKIDLHQ 124
            .:   ||....:..   |.::||:|:||::|.:.:..||:.::.:.|. :.:|::|||||.| ..
  Rat    66 HQ---FPAMQRLSISKGHAFILVFSVTSKQSLDELSPIYKLIVQIKGSVEDIPIMLVGNKCD-ET 126

  Fly   125 ERTVSTEEGKKLAESWRAAFLETSAKQNESVGDIFHQLLIL---------IENENGNPQEKS 177
            :|.|.|.|.:.:|:.|:.||:|||||.|.:|.::|.:||.|         ::.:..|.|:::
  Rat   127 QREVHTREAQAVAQEWKCAFMETSAKMNYNVKELFQELLTLETRRSVSLSVDGKRSNKQKRA 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rheb	NP_730950.2	RheB	5..182	CDD:206709	61/186 (33%)
Diras1	NP_001102457.1	P-loop_NTPase	7..168	CDD:422963	58/164 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0395
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810