DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rheb and Nras

DIOPT Version :9

Sequence 1:NP_730950.2 Gene:Rheb / 117332 FlyBaseID:FBgn0041191 Length:182 Species:Drosophila melanogaster
Sequence 2:NP_542944.1 Gene:Nras / 24605 RGDID:3205 Length:189 Species:Rattus norvegicus


Alignment Length:181 Identity:67/181 - (37%)
Similarity:106/181 - (58%) Gaps:6/181 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 ERHIAMMGYRSVGKSSLCIQFVEGQFVDSYDPTIENTFTKIERVKSQDYIVKLIDTAGQDEYSIF 69
            |..:.::|...||||:|.||.::..|||.||||||:::.|...:..:..::.::|||||:|||..
  Rat     3 EYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAM 67

  Fly    70 PVQYSMDYHGYVLVYSITSQKSFEVVKIIYEKLLDVMGKKYVPVVLVGNKIDLHQERTVSTEEGK 134
            ..||.....|::.|::|.:.|||..:.:..|::..|.....||:||||||.|| ..|||.|::..
  Rat    68 RDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDL-PTRTVDTKQAH 131

  Fly   135 KLAESWRAAFLETSAKQNESVGDIFHQLL-----ILIENENGNPQEKSGCL 180
            :||:|:...|:|||||..:.|.|.|:.|:     ..::..|.:.....||:
  Rat   132 ELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMKKLNSSEDGTQGCM 182

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RhebNP_730950.2 RheB 5..182 CDD:206709 67/181 (37%)
NrasNP_542944.1 H_N_K_Ras_like 3..164 CDD:133338 64/161 (40%)
Effector region 32..40 6/7 (86%)
Hypervariable region. /evidence=ECO:0000250 166..185 3/17 (18%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0395
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.900

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